SYNTHESIS OF THE ANTIPODE OF UDOTEATRIAL HYDRATE USING (+)-GENIPIN AS A CHIRAL BUILDING BLOCK - DETERMINATION OF THE ABSOLUTE-CONFIGURATION OF UDOTEATRIAL HYDRATE

被引：15

作者：

GE, YT

KONDO, S

ODAGAKI, Y

KATSUMURA, S

NAKATANI, K

ISOE, S

机构：

[1] ONO PHARMACEUT CO LTD,MINASE RES INST,OSAKA 618,JAPAN

[2] OSAKA CITY UNIV,FAC SCI,INST ORGAN CHEM,SUMIYOSHI KU,OSAKA 558,JAPAN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 16期

关键词：

GENIPIN; UDOTEATRIAL HYDRATE; MARINE DITERPENE; ABSOLUTE CONFIGURATION; BUILDING BLOCK;

D O I：

10.1016/S0040-4039(00)77640-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Antipode of novel marine diterpenoid udoteatrial hydrate was synthesized from (+)-genipin as a chiral building block via the key intermediate, exo-methylene lactone. This synthesis confirmed the absolute configuration of udoteatrial hydrate as (2R, 3S, 6S, 7S).

引用

页码：2621 / 2624

页数：4

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[2]

Birch A. J., 1972, ADV ORG CHEM, V8, P1

[3]

FIROUZABADI H, 1978, TETRAHEDRON LETT, V19, P839, DOI DOI 10.1016/S0040-4039(01)85412-5

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