STRUCTURAL CARDIAC ABNORMALITIES IN THE FETUS - RELIABILITY OF PRENATAL-DIAGNOSIS AND OUTCOME

Summary. The outcomes of 129 pregnancies in which the fetus was found to have a structural cardiac abnormality are reviewed. Over a 30 month period from January 1985 to June 1987, 1924 patients were referred to the British Heart Foundation Research Centre for Perinatal Cardiology at Guy's Hospital for fetal cardiac seanning. A total of 129 structural cardiac abnormalities was diagnosed; 53% of these patients were referred because of an abnormal ‘four‐chamber view’ on ultrasound at the referring hospital; 47 of the pregnancies (69% of the 68 patients referred before 28 weeks) were terminated, and in the remaining 82 pregnancies outcome was poor with only 20 infants (16%) surviving longer than 11 months. The prenatal diagnosis was fully or partly correct in 96% of the 111 cases where it was possible to verify the diagnosis by post‐mortem or postnatal diagnosis. In the 82 pregnancies not terminated, 13 of the 22 cases given a moderate or good prognosis survived more than 11 months (59% survival), but only seven of the 60 (12% survival) given a fatal, poor or uncertain prognosis. The benefits of a multidisciplinary approach are discussed. Copyright © 1990, Wiley Blackwell. All rights reserved