Mesenchymal Stem Cells and Their Cell Surface Receptors

被引：38

作者：

Docheva, Denitsa ^{[1
]}

Haasters, Florian ^{[1
]}

Schieker, Matthias ^{[1
]}

机构：

[1] LMU, Dept Surg, Expt Surg & Regenerat Med, Munich, Germany

来源：

CURRENT RHEUMATOLOGY REVIEWS | 2008年 / 4卷 / 03期

关键词：

Mesenchymal stem cells (MSCs); receptors; chondrogenic differentiation; osteoarthritis (OA);

D O I：

10.2174/157339708785133479

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Daily increasing evidence indicates that stem cells can be found in nearly every tissue. Mesenchymal stem cells (MSCs) are adult stem cells, which reside in the bone marrow and other mesenchymal tissues. MSCs can be expanded to large numbers and can be driven into diverse mesenchymal cell lineages, including chondrocytes. Therefore, MSCs have attracted the attention of the biomedical community as very promising tools for repair of joint tissues, such as articular cartilage. This review will outline the MSC surface receptors and will focus on receptors that deliver important signals for chondrogenic differentiation of MSCs.

引用

页码：155 / 160

页数：6

共 78 条

[1] Stromal cell-derived factor-1α plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury [J].

Abbott, JD ;

Huang, Y ;

Liu, D ;

Hickey, R ;

Krause, DS ;

Giordano, FJ .

CIRCULATION, 2004, 110 (21) :3300-3305

[2] Chondrogenic differentiation of mesenchymal stem cells from bone marrow: Differentiation-dependent gene expression of matrix components [J].

Barry, F ;

Boynton, RE ;

Liu, BS ;

Murphy, JM .

EXPERIMENTAL CELL RESEARCH, 2001, 268 (02) :189-200

[3] Mesenchymal stem cells: clinical applications and biological characterization [J].

Barry, FP ;

Murphy, JM .

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2004, 36 (04) :568-584

[4] Ex vivo enrichment of mesenchymal cell progenitors by fibroblast growth factor 2 [J].

Bianchi, G ;

Banfi, A ;

Mastrogiacomo, M ;

Notaro, R ;

Luzzatto, L ;

Cancedda, R ;

Quarto, R .

EXPERIMENTAL CELL RESEARCH, 2003, 287 (01) :98-105

[5] Bone marrow stromal stem cells: Nature, biology, and potential applications [J].

Bianco, P ;

Riminucci, M ;

Gronthos, S ;

Robey, PG .

STEM CELLS, 2001, 19 (03) :180-192

[6]

Bobis S, 2006, FOLIA HISTOCHEM CYTO, V44, P215

[7] Molecular phylogeny within type I cytokines and their cognate receptors [J].

Boulay, JL ;

O'Shea, JJ ;

Paul, WE .

IMMUNITY, 2003, 19 (02) :159-163

[8] Novel markers for the prospective isolation of human MSC [J].

Buehring, Hans-Joerg ;

Battula, Venkata Lokesh ;

Treml, Sabrina ;

Schewe, Bernhard ;

Kanz, Lothar ;

Vogel, Wichard .

HEMATOPOIETIC STEM CELLS VI, 2007, 1106 :262-271

[9] Concise review: Mesenchymal stem cells: Their phenotype, differentiation capacity, immunological features, and potential for homing [J].

Chamberlain, Giselle ;

Fox, James ;

Ashton, Brian ;

Middleton, Jim .

STEM CELLS, 2007, 25 (11) :2739-2749

[10] Technology insight: Adult stem cells in cartilage regeneration and tissue engineering [J].

Chen, Faye H. ;

Rousche, Kathleen T. ;

Tuan, Rocky S. .

NATURE CLINICAL PRACTICE RHEUMATOLOGY, 2006, 2 (07) :373-382

← 1 2 3 4 5 6 7 8 →