Practical aspects of leukotriene E(4) assay in the urine

被引：0

作者：

Chabane, MH ^{[1
]}

LeVraux, V ^{[1
]}

LeProvost, AM ^{[1
]}

Leynadier, F ^{[1
]}

机构：

[1] STALLERGENES SA,FRESNES,FRANCE

来源：

ANNALES DE BIOLOGIE CLINIQUE | 1995年 / 53卷 / 10-11期

关键词：

leukotriene E(4); immunoessay; enzyme; allergy; inflammation;

D O I：

暂无

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Leukotrienes constitute a class of potent biological mediators of inflammation arid anaphylaxis. However, their routine assay in various biological fluids is restricted by the complexity of the methodology. Previously this could only be performed by research laboratories with high pressure liquid chromatography and radioimmunological capabilities. The recent availability of kits for immunoenzymatic assay of leukotrienes offers a new tools for clinical laboratories provided the limitations of the method are understood. We suggest a simplified methodology for direct urinary LTE(4) detection and outline a number of areas of concern encountered with this method.

引用

页码：543 / 548

页数：6

共 26 条

[21] TAGARI P, 1989, CLIN CHEM, V35, P388
[22] A COMPARATIVE-STUDY IN ATOPIC SUBJECTS WITH ASTHMA OF THE EFFECTS OF SALMETEROL AND SALBUTAMOL ON ALLERGEN-INDUCED BRONCHOCONSTRICTION, INCREASE IN AIRWAY REACTIVITY, AND INCREASE IN URINARY LEUKOTRIENE-E4 EXCRETION
TAYLOR, IK
OSHAUGHNESSY, KM
CHOUDRY, NB
ADACHI, M
PALMER, JBD
FULLER, RW
[J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1992, 89 (02) : 575 - 583
[23] ELEVATED LEVELS OF LEUKOTRIENE-C4 IN BRONCHOALVEOLAR LAVAGE FLUID FROM ATOPIC ASTHMATICS AFTER ENDOBRONCHIAL ALLERGEN CHALLENGE
WENZEL, SE
LARSEN, GL
JOHNSTON, K
VOELKEL, NF
WESTCOTT, JY
[J]. AMERICAN REVIEW OF RESPIRATORY DISEASE, 1990, 142 (01): : 112 - 119
[24] BRONCHOALVEOLAR LAVAGE FLUID MEDIATOR LEVELS 5 MINUTES AFTER ALLERGEN CHALLENGE IN ATOPIC SUBJECTS WITH ASTHMA - RELATIONSHIP TO THE DEVELOPMENT OF LATE ASTHMATIC RESPONSES
WENZEL, SE
WESTCOTT, JY
LARSEN, GL
[J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1991, 87 (02) : 540 - 548
[25] WESCOTT JY, 1990, J APPL PHYSIOL, V68, P2640
[26] WESCOTT JY, 1993, AM REV RESPIR DIS, V148, P1244

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