TANDEM SILYL MIGRATIONS LEADING TO ALPHA,BETA-BIS-SILYLATED ENALS AND ALPHA,BETA-BIS-SILYLATED ENONES

被引：11

作者：

MERGARDT, B

WEBER, K

ADIWIDJAJA, G

SCHAUMANN, E

机构：

[1] UNIV HAMBURG,INST ORGAN CHEM,W-2000 HAMBURG 13,GERMANY

[2] UNIV HAMBURG,INST MINERAL PETROG,W-2000 HAMBURG 13,GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1991年 / 30卷 / 12期

关键词：

D O I：

10.1002/anie.199116871

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A reaction sequence starting with a silyl-Wittig rearrangement and followed by another 1,2-silyl migration yields the alpha,beta-unsaturated ketones or aldehydes 3 from the alkynyl ethers 1. The beta-alkynols 2 are the intermediates, which in spite of many functional groups are storable at 0-degrees-C. Compounds 2 and 3 are useful synthetic building blocks. (R1 = Me, tBu, CMe2iPr; R = H, Me.)

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页码：1687 / 1688

页数：2

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