Influence of drugs on vitamin D and calcium metabolism

被引：124

作者：

Grober, Uwe ^{[1
]}

Kisters, Klaus ^{[2
,3
]}

机构：

[1] Acad Micronutrient Med, Essen, Germany

[2] Westphalian Wilhelms Univ, Herne, Germany

[3] Acad Micronutrient Med & Hypertens Excellence Ctr, Med Klin 1, Herne, Germany

来源：

DERMATO-ENDOCRINOLOGY | 2012年 / 4卷 / 02期

关键词：

vitamin D; drugs; 25-hydroxy-vitamin D [25(OH)D; pregnane X receptor; 1,25-dihydroxyvitamin D [1,25(OH)(2)D; bisphosphonates; cytostatics; statins;

D O I：

10.4161/derm.20731

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

In the past, interactions between drugs and vitamin D have received only little or no attention in the health care practices. However, since more and more drugs are used for the treatment of patients, this topic is increasingly relevant Several drugs can interfere with the vitamin D and bone metabolism. Drugs that activate the pregnane X receptor can disrupt vitamin D metabolism and vitamin D function. Beside this, the medication oriented supplementation of vitanlin D can ameliorate the pharrnacolgic action of some drugs, such as, bisphosphonates, cytostatics and statins.

引用

页码：158 / 166

页数：9

共 68 条

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