Hematopoietic Stem Cell Development, Niches, and Signaling Pathways

被引：62
作者：
Chotinantakul, Kamonnaree [1 ,2 ]
Leeanansaksiri, Wilairat [1 ,2 ]
机构：
[1] Suranaree Univ Technol, Stem Cell Therapy & Transplantat Res Grp, Nakhon Ratchasima 30000, Thailand
[2] Suranaree Univ Technol, Sch Microbiol, Inst Sci, Nakhon Ratchasima 30000, Thailand
来源：
BONE MARROW RESEARCH | 2012年
关键词：
D O I：
10.1155/2012/270425
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Hematopoietic stem cells (HSCs) play a key role in hematopoietic system that functions mainly in homeostasis and immune response. HSCs transplantation has been applied for the treatment of several diseases. However, HSCs persist in the small quantity within the body, mostly in the quiescent state. Understanding the basic knowledge of HSCs is useful for stem cell biology research and therapeutic medicine development. Thus, this paper emphasizes on HSC origin, source, development, the niche, and signaling pathways which support HSC maintenance and balance between self-renewal and proliferation which will be useful for the advancement of HSC expansion and transplantation in the future.
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页数：16
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共 172 条
[1]   Long-term hematopoietic stem cells require stromal cell-derived factor-1 for colonizing bone marrow during ontogeny [J].
Ara, T ;
Tokoyoda, K ;
Sugiyama, T ;
Egawa, T ;
Kawabata, K ;
Nagasawa, T .
IMMUNITY, 2003, 19 (02) :257-267
[2]   Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche [J].
Arai, F ;
Hirao, A ;
Ohmura, M ;
Sato, H ;
Matsuoka, S ;
Takubo, K ;
Ito, K ;
Koh, GY ;
Suda, T .
CELL, 2004, 118 (02) :149-161
[3]   Notch signaling: Cell fate control and signal integration in development [J].
Artavanis-Tsakonas, S ;
Rand, MD ;
Lake, RJ .
SCIENCE, 1999, 284 (5415) :770-776
[4]   The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes [J].
Balabanian, K ;
Lagane, B ;
Infantino, S ;
Chow, KYC ;
Harriague, J ;
Moepps, B ;
Arenzana-Seisdedos, F ;
Thelen, M ;
Bachelerie, F .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (42) :35760-35766
[5]   RETRACTED: The human placenta is a hematopoietic organ during the embryonic and fetal periods of development (Retracted Article) [J].
Barcena, Alicia ;
Kapidzic, Mirhan ;
Muench, Marcus O. ;
Gormley, Matthew ;
Scott, Marvin A. ;
Weier, Jingly F. ;
Ferlatte, Christy ;
Fisher, Susan J. .
DEVELOPMENTAL BIOLOGY, 2009, 327 (01) :24-33
[6]   Protein phosphatase 2A plays cell-derived factor-1/CXC an important role in stromal chemokine ligand 12-mediated migration and adhesion of CD34+ cells [J].
Basu, Sunanda ;
Ray, Nicole T. ;
Atkinson, Simon J. ;
Broxmeyer, Hal E. .
JOURNAL OF IMMUNOLOGY, 2007, 179 (05) :3075-3085
[7]   ISOLATION OF A CANDIDATE HUMAN HEMATOPOIETIC STEM-CELL POPULATION [J].
BAUM, CM ;
WEISSMAN, IL ;
TSUKAMOTO, AS ;
BUCKLE, AM ;
PEAULT, B .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (07) :2804-2808
[8]   Link controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2 [J].
Bersenev, Alexey ;
Wu, Chao ;
Balcerek, Joanna ;
Tong, Wei .
JOURNAL OF CLINICAL INVESTIGATION, 2008, 118 (08) :2832-2844
[9]   Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells [J].
Bhatia, M ;
Bonnet, D ;
Wu, DM ;
Murdoch, B ;
Wrana, J ;
Gallacher, L ;
Dick, JE .
JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 189 (07) :1139-1147
[10]   Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice [J].
Bhatia, M ;
Wang, JCY ;
Kapp, U ;
Bonnet, D ;
Dick, JE .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (10) :5320-5325
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