BUFURALOL METABOLISM IN HUMAN-LIVER - A SENSITIVE PROBE FOR THE DEBRISOQUINE-TYPE POLYMORPHISM OF DRUG OXIDATION

被引：41

作者：

MINDER, EI ^{[1
]}

MEIER, PJ ^{[1
]}

MULLER, HK ^{[1
]}

MINDER, C ^{[1
]}

MEYER, UA ^{[1
]}

机构：

[1] UNIV HOSP ZURICH,DIV CLIN PHARMACOL CL-25,CH-8091 ZURICH,SWITZERLAND

来源：

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION | 1984年 / 14卷 / 03期

关键词：

D O I：

10.1111/j.1365-2362.1984.tb01121.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：184 / 189

页数：6

共 19 条

[1]

ALVAN G, 1982, LANCET, V1, P333

[2]

BALANT L, 1976, SCHWEIZ MED WSCHR, V106, P1403

[3]

BOOBIS AR, 1983, 2 WORLD C CLIN PHARM

[4] EVIDENCE FOR AN ENZYMATIC DEFECT IN THE 4-HYDROXYLATION OF DEBRISOQUINE BY HUMAN-LIVER [J].

DAVIES, DS ;

KAHN, GC ;

MURRAY, S ;

BRODIE, MJ ;

BOOBIS, AR .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1981, 11 (01) :89-91

[5] THE GENETIC-CONTROL OF BUFURALOL METABOLISM IN MAN [J].

DAYER, P ;

BALANT, L ;

COURVOISIER, F ;

KUPFER, A ;

KUBLI, A ;

GORGIA, A ;

FABRE, J .

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 1982, 7 (01) :73-77

[6]

EICHELBAUM M, 1982, CLIN PHARMACOKINET, V7, P1, DOI 10.2165/00003088-198207010-00001

[7] DETERMINATION OF BUFURALOL AND ITS MAJOR METABOLITES IN PLASMA BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

HAEFELFINGER, P .

JOURNAL OF CHROMATOGRAPHY, 1980, 221 (02) :327-335

[8] ASSAY AND CHARACTERIZATION OF DEBRISOQUINE 4-HYDROXYLASE ACTIVITY OF MICROSOMAL FRACTIONS OF HUMAN-LIVER [J].

KAHN, GC ;

BOOBIS, AR ;

MURRAY, S ;

BRODIE, MJ ;

DAVIES, DS .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1982, 13 (05) :637-645

[9] THE UPJOHN-AWARD-LECTURE 1981 - THE METABOLISM OF XENOBIOTICS IN DIFFERENT POPULATIONS [J].

KALOW, W .

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1982, 60 (01) :1-12

[10]

KAPITULNIK J, 1977, CLIN PHARMACOL THER, V21, P166

← 1 2 →