ENVIRONMENTAL RISK-FACTORS AND MULTIPLE-SCLEROSIS - A COMMUNITY-BASED, CASE-CONTROL STUDY IN THE PROVINCE OF FERRARA, ITALY

被引：78

作者：

CASETTA, I ^{[1
]}

GRANIERI, E ^{[1
]}

MALAGU, S ^{[1
]}

TOLA, MR ^{[1
]}

PAOLINO, E ^{[1
]}

CANIATTI, LM ^{[1
]}

GOVONI, V ^{[1
]}

MONETTI, VC ^{[1
]}

FAINARDI, E ^{[1
]}

机构：

[1] UNIV FERRARA, INST NEUROL, I-44100 FERRARA, ITALY

来源：

NEUROEPIDEMIOLOGY | 1994年 / 13卷 / 03期

关键词：

MULTIPLE SCLEROSIS; EPIDEMIOLOGY; RISK FACTORS;

D O I：

10.1159/000110369

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The frequency of multiple sclerosis (MS) in Italy and in other areas of the world seems to have increased over time, suggesting that some environmental factors operate in its etiology. We performed a retrospective, community-based case-control study on MS in order to verify the etiologic role of selected environmental factors. We found an association between MS and higher educational level, employment in public administration, past history of allergies, and infection at an early age with measles, rubella and whooping cough. Our data seem to confirm that exogenous factors play a role in the etiology of MS although some confounding variables could have accounted for the associations.

引用

页码：120 / 128

页数：9

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