FUSION PROTEINS WITH MULTIPLE COPIES OF THE MAJOR ANTIGENIC DETERMINANT OF FOOT-AND-MOUTH-DISEASE VIRUS PROTECT BOTH THE NATURAL HOST AND LABORATORY-ANIMALS

被引：77
作者：
BROEKHUIJSEN, MP
VANRIJN, JMM
BLOM, AJM
POUWELS, PH
ENGERVALK, BE
BROWN, F
FRANCIS, MJ
机构：
[1] WELLCOME BIOTECHNOL LTD,ASH RD,WOKING GU24 0NQ,SURREY,ENGLAND
[2] TNO,MED BIOL LAB,2280 AA RIJSWIJK,NETHERLANDS
来源：
JOURNAL OF GENERAL VIROLOGY | 1987年 / 68卷
关键词：
D O I：
10.1099/0022-1317-68-12-3137
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：3137 / 3143
页数：7
相关论文
共 29 条
  • [1] BACHRACH HL, 1975, J IMMUNOL, V115, P1636
  • [2] PROTECTION AGAINST FOOT-AND-MOUTH-DISEASE BY IMMUNIZATION WITH A CHEMICALLY SYNTHESIZED PEPTIDE PREDICTED FROM THE VIRAL NUCLEOTIDE-SEQUENCE
    BITTLE, JL
    HOUGHTEN, RA
    ALEXANDER, H
    SHINNICK, TM
    SUTCLIFFE, JG
    LERNER, RA
    ROWLANDS, DJ
    BROWN, F
    [J]. NATURE, 1982, 298 (5869) : 30 - 33
  • [3] SYNTHESIS OF FUSION PROTEINS WITH MULTIPLE COPIES OF AN ANTIGENIC DETERMINANT OF FOOT-AND-MOUTH-DISEASE VIRUS
    BROEKHUIJSEN, MP
    BLOM, T
    VANRIJN, J
    POUWELS, PH
    KLASEN, EA
    FASBENDER, MJ
    ENGERVALK, BE
    [J]. GENE, 1986, 49 (02) : 189 - 197
  • [4] SYNTHESIS OF FUSION PROTEINS CONTAINING ANTIGENIC DETERMINANTS OF FOOT-AND-MOUTH-DISEASE VIRUS
    BROEKHUIJSEN, MP
    BLOM, T
    KOTTENHAGEN, M
    POUWELS, PH
    MELOEN, RH
    BARTELING, SJ
    ENGERVALK, BE
    [J]. VACCINE, 1986, 4 (02) : 119 - 124
  • [5] VACCINATION AGAINST FOOT-AND-MOUTH-DISEASE - PAST, PRESENT AND FUTURE
    BROWN, F
    [J]. ANNALES DE L INSTITUT PASTEUR-VIROLOGY, 1985, 136E (04): : 547 - 552
  • [6] PROTECTION OF CATTLE AGAINST FOOT-AND-MOUTH-DISEASE BY A SYNTHETIC PEPTIDE
    DIMARCHI, R
    BROOKE, G
    GALE, C
    CRACKNELL, V
    DOEL, T
    MOWAT, N
    [J]. SCIENCE, 1986, 232 (4750) : 639 - 641
  • [7] CIRCUMSPOROZOITE GENE OF PLASMOIDIUM-CYNOMOLGI (GOMBAK) - CDNA CLONING AND EXPRESSION OF THE REPETITIVE CIRCUMSPOROZOITE EPITOPE
    ENEA, V
    ARNOT, D
    SCHMIDT, EC
    COCHRANE, A
    GWADZ, R
    NUSSENZWEIG, RS
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (23): : 7520 - 7524
  • [8] FRANCIS MJ, 1987, IMMUNOLOGY, V61, P1
  • [9] IMMUNOLOGICAL PRIMING WITH SYNTHETIC PEPTIDES OF FOOT-AND-MOUTH-DISEASE VIRUS
    FRANCIS, MJ
    FRY, CM
    ROWLANDS, DJ
    BROWN, F
    BITTLE, JL
    HOUGHTEN, RA
    LERNER, RA
    [J]. JOURNAL OF GENERAL VIROLOGY, 1985, 66 (NOV) : 2347 - 2354
  • [10] ANTIBODY-RESPONSE IN PIG NASAL FLUID AND SERUM FOLLOWING FOOT-AND-MOUTH-DISEASE INFECTION OR VACCINATION
    FRANCIS, MJ
    BLACK, L
    [J]. JOURNAL OF HYGIENE, 1983, 91 (02) : 329 - 334
123