Choroidal Neovascularization in a Patient with Crohn's Disease

被引：2

作者：

Casalino, Giuseppe ^{[1
]}

Querques, Giuseppe ^{[1
]}

Corvi, Federico ^{[1
]}

Borrelli, Enrico ^{[1
]}

Triolo, Giacinto ^{[1
]}

Ramirez, Giuseppe Alvise ^{[2
]}

Bandello, Francesco ^{[1
]}

机构：

[1] Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Dept Ophthalmol, Milan, Italy

[2] Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Dept Immunol, Milan, Italy

来源：

CASE REPORTS IN OPHTHALMOLOGY | 2014年 / 5卷 / 02期

关键词：

Choroidal neovascularization; Crohn's disease; Anti-VEGF; Intravitreal ranibizumab; Fluorescein angiography; Optical coherence tomography;

D O I：

10.1159/000365881

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To report a case of subfoveal choroidal neovascularization (CNV) in a patient with Crohn's disease (CD) and to discuss a possible association between these two conditions. Methods: This is an observational case report. Results: A 69-year-old male affected by CD was referred to our department because of sudden visual acuity drop in the left eye. A subfoveal CNV was diagnosed based on slit-lamp fundus biomicroscopy and fluorescein angiography. Color fundus photography, infrared autofluorescence and spectral-domain optical coherence tomography imaging of both eyes were also performed. Following six intravitreal ranibizumab injections, visual improvement was obtained with no related adverse events. Conclusion: We report a case of CNV as a possible rare extraintestinal manifestation of CD. The use of ranibizumab successfully impacted on CNV, while not affecting CD, which remained quiescent. (C) 2014 S. Karger AG, Basel

引用

页码：249 / 254

页数：6

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