Invasive Pulmonary Aspergillosis in Acute Leukemia: Current Issues for Pathogenesis, Diagnosis and Treatment

被引：1
作者：
Ali, Ridvan [1 ]
Ozcelik, Tulay [1 ]
机构：
[1] Uludag Univ, Sch Med, Dept Internal Med, Div Hematol, TR-16059 Gorukle, Bursa, Turkey
来源：
CURRENT RESPIRATORY MEDICINE REVIEWS | 2006年 / 2卷 / 01期
关键词：
Invasive pulmonary aspergillosis (IPA); acute leukemia;
D O I：
10.2174/157339806775486191
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Invasive pulmonary aspergillosis (IPA) is a frequently life-threatening fungal infection that complicates acute leukemia patients following conventional chemotherapy and bone marrow transplantation. The mortality rate reaches 50% in leukemic patients during chemotherapy-induced neutropenia and can exceed 90% in bone marrow transplantation patients. Despite advances in antimicrobial therapy and supportive care, IPA remains a major clinical problem in patients with acute leukemia. Current issues for IPA in adults are reviewed.
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页码：3 / 13
页数：11
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