ANTIGEN PROCESSING AND PRESENTATION INVIVO - THE MICROENVIRONMENT AS A CRUCIAL FACTOR

被引：79

作者：

VANROOIJEN, N

机构：

来源：

IMMUNOLOGY TODAY | 1990年 / 11卷 / 12期

关键词：

D O I：

10.1016/0167-5699(90)90171-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Antigen processing and presentation in vitro is an increasingly well understood phenomenon. However, in vivo, a large number of variables conspire to obscure and confuse. In this article, Nico van Rooijen attempts to bring order to events that occur in the spleen after antigenic challenge: starting with the large body of reliable in vitro data he incorporates information on splenic anatomy, cell trafficking and the cellular microenvironment to arrive at a physiological model for antigen handling in vivo.

引用

页码：436 / 439

页数：4

共 41 条

[1] A REASSESSMENT OF THE MECHANISMS OF ANTIGEN-SPECIFIC T-CELL-DEPENDENT B-CELL ACTIVATION [J].