TESTING OF SUSCEPTIBILITY OF MYCOBACTERIUM-TUBERCULOSIS TO PYRAZINAMIDE - COMPARISON OF BACTEC METHOD WITH PYRAZINAMIDASE ASSAY

被引：50
作者：
MILLER, MA
THIBERT, L
DESJARDINS, F
SIDDIQI, SH
DASCAL, A
机构：
[1] LAB SANTE PUBL QUEBEC, Ste Anne De Bellevue, PQ, CANADA
[2] BECTON DICKINSON DIAGNOST INSTRUMENT SYST, SPARKS, MD 21152 USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 1995年 / 33卷 / 09期
关键词：
D O I：
10.1128/JCM.33.9.2468-2470.1995
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The susceptibility of 428 clinical isolates of Mycobacterium tuberculosis to pyrazinamide was assessed by the Bactec method and the Wayne pyrazinamidase assay. The correlation between the two tests was 98.2 and 100% for susceptible and resistant strains, respectively. False resistance was seen in four (0.8%) strains with the Bactec test, and false-susceptible results occurred in two (0.5%) pyrazinamidase assays. The Bactec test is rapid and reliable, and the Bactec results correlate well with the pyrazinamidase test results, although some strains did not grow web in the test medium.
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收藏
页码：2468 / 2470
页数：3
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