TREMORGENIC MYCOTOXINS PRODUCED BY STRAINS OF PENICILLIUM SPP ISOLATED FROM TOXIC POA-HUECU-PARODI

被引：9

作者：

SCUTERI, M ^{[1
]}

DEMIGUEL, MAS ^{[1
]}

VIERA, JB ^{[1
]}

DEBANCHERO, EP ^{[1
]}

机构：

[1] INST NACL TECHNOL AGROPECUARIA,CTR INVEST CIENCIAS VET,INST ANIM PETHOL,RA-1712 BUENOS AIRES,ARGENTINA

来源：

MYCOPATHOLOGIA | 1992年 / 120卷 / 03期

关键词：

PENICILLIUM SPP; GROWTH INVITRO; TREMORGENIC MYCOTOXINS; POA-HUECU PARODI;

D O I：

10.1007/BF00436396

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Seventeen strains of Penicillium spp. have been isolated from Poa huecu Parodi from the Zapala zone, exhibiting toxicity to sheet. The following strains have been identified: P. crustosum, cyclopium, notatum, palitans, puberulum, verrucosum, viridicatum and Penicillium spp. The toxigenic capacity of the strains was studied after growing them under suitable conditions. Toxins produced were analysed by thin layer chromatography (TLC). Penitrem A (PA) and Penitrem B (PB) neurotoxins were identified and quantitated in twelve strains; verruculogen (VERR) and fumitremorgen B (FTB) being present in one of them. The effect of these mycotoxins was studied in mice. Neurological symptoms characteristic of the intoxication by tremorgenic toxins and similar to those observed in sheep suffering from 'huecu's disease' were observed. The possible role of these toxins as causative agents of 'huecu's disease' is discussed.

引用

页码：177 / 182

页数：6