PROTEIN FOLDING - CONSTRUCTION OF FUNCTIONAL STRUCTURE

被引:5
作者
KIHO, Y
机构
[1] Central Research Institute, Ishihara Sangyo Kaisha, Ltd., Kusatsu
关键词
PROTEIN FOLDING;
D O I
10.1247/csf.16.45
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The problem of protein folding was studied with trypsin inhibitor by deviation analysis (1). The results showed that: i) Qualitatively, the main features of the structure, determined by this method, coincided with the structure determined by X-ray crystallography (3). This structure is, however, not topological but functional, and may elucidate the functional relations between various parts of the protein.
引用
收藏
页码:45 / 48
页数:4
相关论文
共 50 条
  • [31] Effect of Macromolecular Crowding on Protein Folding Dynamics at the Secondary Structure Level
    Mukherjee, Smita
    Waegele, Matthias M.
    Chowshury, Pramit
    Guo, Lin
    Gai, Feng
    JOURNAL OF MOLECULAR BIOLOGY, 2009, 393 (01) : 227 - 236
  • [32] CONTRIBUTION OF COTRANSLATIONAL FOLDING TO THE RATE OF FORMATION OF NATIVE PROTEIN-STRUCTURE
    FEDOROV, AN
    BALDWIN, TO
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (04) : 1227 - 1231
  • [33] Radical approaches to probe protein structure, folding, and interactions by mass spectrometry
    Maleknia, SD
    Downard, K
    MASS SPECTROMETRY REVIEWS, 2001, 20 (06) : 388 - 401
  • [34] Hydrophobic folding units at protein-protein interfaces: Implications to protein folding and to protein-protein association
    Tsai, CJ
    Nussinov, R
    PROTEIN SCIENCE, 1997, 6 (07) : 1426 - 1437
  • [35] Thiamin and protein folding
    Lonsdale, Derrick
    MEDICAL HYPOTHESES, 2019, 129
  • [36] The protein folding network
    Rao, F
    Caflisch, A
    JOURNAL OF MOLECULAR BIOLOGY, 2004, 342 (01) : 299 - 306
  • [37] Protein folding: The endgame
    Levitt, M
    Gerstein, M
    Huang, E
    Subbiah, S
    Tsai, J
    ANNUAL REVIEW OF BIOCHEMISTRY, 1997, 66 : 549 - 579
  • [38] Protein folding: Then and now
    Chen, Yiwen
    Ding, Feng
    Nie, Huifen
    Serohijos, Adrian W.
    Sharma, Shantanu
    Wilcox, Kyle C.
    Yin, Shuangye
    Dokholyan, Nikolay V.
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2008, 469 (01) : 4 - 19
  • [39] Protein folding and diseases
    Lee, C
    Yu, MH
    JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2005, 38 (03): : 275 - 280
  • [40] On the entropy of protein folding
    Makhatadze, GI
    Privalov, PL
    PROTEIN SCIENCE, 1996, 5 (03) : 507 - 510