2 TNF RECEPTORS

被引:1025
|
作者
TARTAGLIA, LA
GOEDDEL, DV
机构
[1] Genentech, South San Francisco, CA 94080
来源
IMMUNOLOGY TODAY | 1992年 / 13卷 / 05期
关键词
D O I
10.1016/0167-5699(92)90116-O
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In the past few years, considerable progress has been made on the identification and characterization of tumor necrosis factor (TNF) receptors. The relative roles played by the two receptor types in signaling the diverse functions of TNF are less clear. Here, Louis Tartaglia and David Goeddel summarize progress to date and propose a model of TNF receptor triggering that reconciles the seemingly conflicting data.
引用
收藏
页码:151 / 153
页数:3
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