Negative-pressure wound therapy for management of diabetic foot wounds: a review of the mechanism of action, clinical applications, and recent developments

被引：62
作者：
Hasan, Muhammed Y. [1 ]
Teo, Rachel [1 ]
Nather, Aziz [1 ]
机构：
[1] Natl Univ Singapore Hosp, Dept Orthopaed Surg, Div Foot & Ankle, 1E Lower Kent Ridge Rd,NUHS Tower Block,Level 11, Singapore 119228, Singapore
来源：
DIABETIC FOOT & ANKLE | 2015年 / 6卷 / 01期
关键词：
vacuum therapy; subatmospheric pressure dressing; topical negative-pressure therapy; diabetic ulcers; wound bed preparation; amputation;
D O I：
10.3402/dfa.v6.27618
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Negative-pressure wound therapy (NPWT) plays an important role in the treatment of complex wounds. Its effect on limb salvage in the management of the diabetic foot is well described in the literature. However, a successful outcome in this subgroup of diabetic patients requires a multidisciplinary approach with careful patient selection, appropriate surgical debridement, targeted antibiotic therapy, and optimization of healing markers. Evolving NPWT technology including instillation therapy, nanocrystalline adjuncts, and portable systems can further improve results if used with correct indications. This review article summarizes current knowledge about the role of NPWT in the management of the diabetic foot and its mode of action, clinical applications, and recent developments.
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页数：10
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