Negative-pressure wound therapy for management of diabetic foot wounds: a review of the mechanism of action, clinical applications, and recent developments

被引：62
作者：
Hasan, Muhammed Y. [1 ]
Teo, Rachel [1 ]
Nather, Aziz [1 ]
机构：
[1] Natl Univ Singapore Hosp, Dept Orthopaed Surg, Div Foot & Ankle, 1E Lower Kent Ridge Rd,NUHS Tower Block,Level 11, Singapore 119228, Singapore
来源：
DIABETIC FOOT & ANKLE | 2015年 / 6卷 / 01期
关键词：
vacuum therapy; subatmospheric pressure dressing; topical negative-pressure therapy; diabetic ulcers; wound bed preparation; amputation;
D O I：
10.3402/dfa.v6.27618
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Negative-pressure wound therapy (NPWT) plays an important role in the treatment of complex wounds. Its effect on limb salvage in the management of the diabetic foot is well described in the literature. However, a successful outcome in this subgroup of diabetic patients requires a multidisciplinary approach with careful patient selection, appropriate surgical debridement, targeted antibiotic therapy, and optimization of healing markers. Evolving NPWT technology including instillation therapy, nanocrystalline adjuncts, and portable systems can further improve results if used with correct indications. This review article summarizes current knowledge about the role of NPWT in the management of the diabetic foot and its mode of action, clinical applications, and recent developments.
引用
收藏
页数：10
相关论文
共 60 条
  • [1] Vacuum-assisted closure: A new method for wound control and treatment: Clinical experience
    Argenta, LC
    Morykwas, MJ
    [J]. ANNALS OF PLASTIC SURGERY, 1997, 38 (06) : 563 - 576
  • [2] Armstrong David G, 2002, Ostomy Wound Manage, V48, P64
  • [3] Comparative effectiveness of mechanically and electrically powered negative pressure wound therapy devices: A multicenter randomized controlled trial
    Armstrong, David G.
    Marston, William A.
    Reyzelman, Alexander M.
    Kirsner, Robert S.
    [J]. WOUND REPAIR AND REGENERATION, 2012, 20 (03) : 332 - 341
  • [4] Negative pressure wound therapy after partial diabetic foot amputation: a multicentre, randomised controlled trial
    Armstrong, DG
    Lavery, LA
    [J]. LANCET, 2005, 366 (9498) : 1704 - 1710
  • [5] Bernstein BH, 2005, WOUNDS, V17, P37
  • [6] BERNSTEIN L, 1995, NUTRITION, V11, P169
  • [7] Evidence-based recommendations for negative pressure wound therapy: Treatment variables (pressure levels, wound filler and contact layer) - Steps towards an international consensus
    Birke-Sorensen, H.
    Malmsjo, M.
    Rome, P.
    Hudson, D.
    Krug, E.
    Berg, L.
    Bruhin, A.
    Caravaggi, C.
    Chariker, M.
    Depoorter, M.
    Dowsett, C.
    Dunn, R.
    Duteille, F.
    Ferreira, F.
    Francos Martinez, J. M.
    Grudzien, G.
    Ichioka, S.
    Ingemansson, R.
    Jeffery, S.
    Lee, C.
    Vig, S.
    Runkel, N.
    Martin, R.
    Smith, J.
    [J]. JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 2011, 64 : S1 - S16
  • [8] Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: A multicenter randomized controlled trial
    Blume, Peter A.
    Walters, Jodi
    Payne, Wyatt
    Ayala, Jose
    Lantis, John
    [J]. DIABETES CARE, 2008, 31 (04) : 631 - 636
  • [9] The Influence of Low and High Pressure Levels during Negative-Pressure Wound Therapy on Wound Contraction and Fluid Evacuation
    Borgquist, Ola
    Ingemansson, Richard
    Malmsjo, Malin
    [J]. PLASTIC AND RECONSTRUCTIVE SURGERY, 2011, 127 (02) : 551 - 559
  • [10] Borgquist O, 2009, WOUNDS, V21, P302
123456