TH1 AND TH2 CD4(+) T-CELLS IN THE PATHOGENESIS OF ORGAN-SPECIFIC AUTOIMMUNE-DISEASES

被引：1085

作者：

LIBLAU, RS ^{[1
]}

SINGER, SM ^{[1
]}

MCDEVITT, HO ^{[1
]}

机构：

[1] HARVARD UNIV, SCH MED, DEPT BIOL CHEM & MOLEC PHARMACOL, BOSTON, MA 02115 USA

来源：

IMMUNOLOGY TODAY | 1995年 / 16卷 / 01期

关键词：

D O I：

10.1016/0167-5699(95)80068-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

CD4(+) T cells play a Key role in regulating immune system function. When these regulatory processes go awry, organ-specific autoimmune diseases may develop. Here, Roland Liblau, Steven Singer and Hugh McDevitt explore the thesis that a particular subset of CD4(+) T cells, namely T helper 1 (Th1) cells, contributes to the pathogenesis of organ-specific autoimmune diseases, while another subset, Th2 cells, prevents them.

引用

页码：34 / 38

页数：5

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