HUMAN CHROMOSOME-21 - GENOME MAPPING AND EXPLORATION, CIRCA 1993

被引:74
作者
ANTONARAKIS, SE [1 ]
机构
[1] UNIV GENEVA,DIV MED GENET,CH-1211 GENEVA 4,SWITZERLAND
关键词
D O I
10.1016/0168-9525(93)90210-9
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Chromosome 21 is the smallest human chromosome, but one of considerable medical importance. A comprehensive physical map of overlapping YACs, a dense linkage map and an almost complete long-range restriction map have been produced much earlier than expected. These mapping accomplishments will greatly facilitate the exploration of chromosome 21, helping to characterize both genes and their impact in beafth and disease.
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页码:142 / 148
页数:7
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