The Salivary Gland and Systemic Health : Towards the Creation of Salivary Gland and Health Medicine

被引：4
作者：
Tsukinoki, Keiichi [1 ]
Saruta, Juri [2 ]
Yamano, Seiichi [3 ]
Tomita, Masaru [4 ]
机构：
[1] Kanagawa Dent Coll, Inst Salivary Gland & Hlth Med, Dept Maxillofacial Diagnost Sci, Div Pathol & Res, 82 Inaoka, Yokosuka, Kanagawa 2388580, Japan
[2] Kanagawa Dent Coll, Dept Craniofacial Dev Dent, Div Orthodont, Yokosuka, Kanagawa 2388580, Japan
[3] NYU, Coll Dent, Dept Prosthodont, New York, NY 10010 USA
[4] Keio Univ, Inst Adv Biosci, Tokyo, Japan
来源：
JOURNAL OF ORAL BIOSCIENCES | 2011年 / 53卷 / 04期
关键词：
salivary gland; saliva; BDNF; gene therapy; metabolomics;
D O I：
10.2330/joralbiosci.53.330
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Salivary glands are intimately connected with the entire body via the nervous system and blood vessels, yet few studies have documented the effects of the salivary glands on the health of the whole body, although saliva has often been reported to possibly contain promising biomarkers of systemic disease states, including cancer. We therefore propose that the investigation of the effects of the salivary gland on the whole body and vice versa could introduce a new field of study, i.e., "salivary gland and health medicine." This review examines data from novel studies on "salivary gland and health medicine" that were carried out by 3 different research groups.
引用
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页码：330 / 337
页数：8
相关论文
共 36 条
  • [1] AGGRESSIVE-BEHAVIOR INDUCES RELEASE OF NERVE GROWTH-FACTOR FROM MOUSE SALIVARY-GLAND INTO THE BLOOD-STREAM
    ALOE, L
    ALLEVA, E
    BOHM, A
    LEVIMONTALCINI, R
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (16) : 6184 - 6187
  • [2] EMOTIONAL-STRESS INDUCED BY PARACHUTE JUMPING ENHANCES BLOOD NERVE GROWTH-FACTOR LEVELS AND THE DISTRIBUTION OF NERVE GROWTH-FACTOR RECEPTORS IN LYMPHOCYTES
    ALOE, L
    BRACCILAUDIERO, L
    ALLEVA, E
    LAMBIASE, A
    MICERA, A
    TIRASSA, P
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (22) : 10440 - 10444
  • [3] Salivary glands: novel target sites for gene therapeutics
    Baum, BJ
    Voutetakis, A
    Wang, JH
    [J]. TRENDS IN MOLECULAR MEDICINE, 2004, 10 (12) : 585 - 590
  • [4] Development of a gene transfer-based treatment for radiation-induced salivary hypofunction
    Baum, Bruce J.
    Zheng, Changyu
    Alevizos, Ilias
    Cotrim, Ana P.
    Liu, Shuying
    McCullagh, Linda
    Goldsmith, Corinne M.
    McDermott, Nancy
    Chiorini, John A.
    Nikolov, Nikolay P.
    Illei, Gabor G.
    [J]. ORAL ONCOLOGY, 2010, 46 (01) : 4 - 8
  • [5] SJOGRENS SYNDROME - A CLINICAL PATHOLOGICAL AND SEROLOGICAL STUDY OF 62 CASES
    BLOCH, KJ
    BUCHANAN, WW
    WOHL, MJ
    BUNIM, JJ
    [J]. MEDICINE, 1965, 44 (03) : 187 - +
  • [6] Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands
    Delporte, C
    OConnell, BC
    He, XJ
    Lancaster, HE
    OConnell, AC
    Agre, P
    Baum, BJ
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (07) : 3268 - 3273
  • [7] Periodontal disease as a risk marker in coronary heart disease and chronic kidney disease
    Fisher, Monica A.
    Borgnakke, Wenche S.
    Taylor, George W.
    [J]. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2010, 19 (06) : 519 - 526
  • [8] GENE THERAPY FOR HUMAN GENETIC DISEASE
    FRIEDMANN, T
    ROBLIN, R
    [J]. SCIENCE, 1972, 175 (4025) : 949 - +
  • [9] Presence and localization of neurotrophins and neurotrophin receptors in rat lacrimal gland
    Ghinelli, E
    Johansson, J
    Ríos, JD
    Chen, LL
    Zoukhri, D
    Hodges, RR
    Dartt, DA
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2003, 44 (08) : 3352 - 3357
  • [10] Using salivary glands as a tissue target for gene therapeutics
    Hoque, ATMS
    Yamano, S
    Baccaglini, L
    Baum, BJ
    [J]. JOURNAL OF DRUG TARGETING, 2001, 9 (06) : 485 - 494
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