TREATMENT OF ACUTE MOUNTAIN-SICKNESS - HYPERBARIC VERSUS OXYGEN-THERAPY

被引：38

作者：

KASIC, JF

YARON, M

NICHOLAS, RA

LICKTEIG, JA

ROACH, R

机构：

[1] Department of Chemical Engineering, University of Colorado, Boulder, CO

[2] Section of Emergency Medicine and Trauma, University of Colorado Health Sciences Center, Denver, CO

[3] University of Colorado Health Sciences Center, Snake River Health Clinic, Keystone, CO

[4] Cardinal Stritch College, Milwaukee, WI

[5] Lovelace Medical Foundation, Albuquerque, NM

来源：

ANNALS OF EMERGENCY MEDICINE | 1991年 / 20卷 / 10期

关键词：

acute mountain sickness; treatment;

D O I：

10.1016/S0196-0644(05)81385-X

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Study objectives: To compare the benefits of simulated descent in a hyperbaric chamber with those of supplementary oxygen for the treatment of acute mountain sickness. Design: A prospective study. Setting: The Snake River Health Clinic in Keystone, Colorado, which has an altitude of 2,850 m (9,300 ft). Type of participants: Twenty-four patients who presented with acute mountain sickness. Interventions: A simulated descent of 1,432 m (4,600 ft) was attained by placing the patients in a fabric hyperbaric chamber and pressurizing the chamber to 120 mm Hg (2.3 PSI) above ambient pressure. Patients were randomly assigned to either the hyperbaric treatment or treatment with 4 L of oxygen given by facemask; both treatments lasted for two hours. Measurements and main results: Mean arterial oxygen saturation (Sao2) increased 7% (84 +/- 2% to 91 +/- 1%) with pressurization and 14% (83 +/- 4% to 96 +/- 1%) with oxygen during treatment over pretreatment levels. Symptoms of acute mountain sickness decreased as rapidly with pressurization as with oxygen treatment, despite significantly higher Sao2 in the oxygen-treated group during treatment. Symptomatic improvement was retained in both groups at least one hour after treatment. Conclusion: Simulated descent in a fabric hyperbaric chamber is as effective as oxygen therapy for the immediate relief of acute mountain sickness.

引用

页码：1109 / 1112

页数：4

共 19 条

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