IN-VIVO EFFECTS OF RUFLOXACIN AND CIPROFLOXACIN ON T-CELL SUBSETS AND TUMOR-NECROSIS-FACTOR PRODUCTION IN MICE INFECTED WITH BACTEROIDES-FRAGILIS

被引：17

作者：

GOLLAPUDI, SV ^{[1
]}

CHUAH, SK ^{[1
]}

HARVEY, T ^{[1
]}

THADEPALLI, HD ^{[1
]}

THADEPALLI, H ^{[1
]}

机构：

[1] UCI, SCH MED, IRVINE, CA 92717 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 08期

关键词：

D O I：

10.1128/AAC.37.8.1711

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We investigated the in vivo effects of rufloxacin and ciprofloxacin on T-cell subsets and tumor necrosis factor production in mice infected with Bacteroides fragilis. These quinolones did not alter the helper/suppressor ratio but did modulate the kinetics of tumor necrosis factor production in infected animals. This result correlated with the observed therapeutic efficacies of the quinolones.

引用

收藏

页码：1711 / 1712

页数：2

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