MOLECULAR LINKAGE OF HANTAVIRUS PULMONARY SYNDROME TO THE WHITE-FOOTED MOUSE, PERMYSCUS-LEUCOPUS - GENETIC-CHARACTERIZATION OF THE M-GENOME OF NEW-YORK-VIRUS

被引：99

作者：

HJELLE, B

LEE, SW

SONG, WM

TORREZMARTINEZ, N

SONG, JW

YANAGIHARA, R

GAVRILOVSKAYA, I

MACKOW, ER

机构：

[1] UNIV NEW MEXICO, HLTH SCI CTR, CTR CANC RES & TREATMENT, ALBUQUERQUE, NM 87131 USA

[2] UNITED BLOOD SERV, ALBUQUERQUE, NM USA

[3] SUNY STONY BROOK, STONY BROOK, NY 11794 USA

[4] VET ADM MED CTR, NORTHPORT, NY 11768 USA

[5] NINCDS, BETHESDA, MD 20892 USA

来源：

JOURNAL OF VIROLOGY | 1995年 / 69卷 / 12期

关键词：

D O I：

10.1128/JVI.69.12.8137-8141.1995

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The complete M segment sequences of hantaviruses amplified from tissues of a patient with hantavirus pulmonary syndrome in the northeastern United States and from white-footed mice, Peromyscus leucopus, from New York were 99% identical and differed from those of Four Corners virus by 23%. The serum of this patient failed to recognize a conserved, immunodominant epitope of the Four Corners virus G1 glycoprotein. Collectively, these findings indicate that P. leucopus harbors a genetically and antigenically distinct hantavirus that causes hantavirus pulmonary syndrome.

引用

页码：8137 / 8141

页数：5