RELATIONSHIP BETWEEN GENETIC-FACTORS AND IMMUNE-RESPONSE IN PSORIASIS PATIENTS

被引：0
|
作者：
RAKHMATOV, AB [1 ]
ZALYALIYEVA, MV [1 ]
CHICHENINA, IV [1 ]
GUSEVA, LI [1 ]
BODROVA, NN [1 ]
BELYKH, OV [1 ]
机构：
[1] MINIST PUBL HLTH UZSSR,INST HEMATOL & BLOOD TRANSFUS,CTR IMMUNOL CLASS,TASHKENT,UZBEKISTAN,USSR
来源：
VESTNIK DERMATOLOGII I VENEROLOGII | 1991年 / 02期
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Tissue typing of HLA system A, B, C locuses was carried out with the lymphocyte toxic method developed by Terasaki and McLelland in 296 psoriasis patients, 197 of them Uzbeks. In 65 psoriasis patients (Uzbeks) cellular and humoral immunity parameters were examined. Elevated detection rate of HLA system antigens A1, A11, B13, B17, B21, Cw3 was revealed in psoriasis patients both Uzbeks and representatives of other nationalities. The Uzbek and non-Uzbek patients with psoriasis differed in respect of HLA-A19 and HLA-B14 antigens. A relationship between immunogenetic factors and immune response manifectation has been revealed in psoriasis patients: a marked deficit of T lymphocytes, T helpers, T suppressors, and immunoregulatory subpopulation ratio index are observed in the presence of HLA B13, Cw3, B17 antigens; IgA immunodeficiency is also associated with these antigens.
引用
收藏
页码：30 / 33
页数：4
相关论文
共 50 条
  • [1] GENETIC-FACTORS IN PSORIASIS
    MORDOVTSEV, VN
    SERGEYEV, AS
    ALIEVA, PM
    INTERNATIONAL JOURNAL OF DERMATOLOGY, 1981, 20 (02) : 99 - 101
  • [2] THE INFLUENCE OF GENETIC-FACTORS ON THE IMMUNE-RESPONSE AS JUDGED BY PNEUMOCOCCAL VACCINATION OF MONOZYGOTIC AND DIZYGOTIC CAUCASIAN TWINS
    KONRADSEN, HB
    HENRICHSEN, J
    WACHMANN, H
    HOLM, N
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 1993, 92 (03): : 532 - 536
  • [3] RELATIONSHIP BETWEEN HL-A FACTORS AND STRENGTH OF IMMUNE-RESPONSE
    CURTONI, ES
    MATTIUZ, PL
    SCUDELLE.G
    ATTI ASSOCIAZIONE GENETICA ITALIANA, 1973, 18 : 94 - 96
  • [4] TAXOPLASMA ENCEPHALITIS IN CONGENIC B10 AND BALB MICE - IMPACT OF GENETIC-FACTORS ON THE IMMUNE-RESPONSE
    DECKERTSCHLUTER, M
    SCHLUTER, D
    SCHMIDT, D
    SCHWENDEMANN, G
    WIESTLER, OD
    HOF, H
    INFECTION AND IMMUNITY, 1994, 62 (01) : 221 - 228
  • [5] RELATIONSHIP BETWEEN IMMUNE-RESPONSE AND CLINICAL MANIFESTATIONS IN PATIENTS WITH TUBERCULOSIS
    FONSECA, LS
    KRITSKI, A
    ANNA, CS
    JANINI, MC
    FERREIRA, MAS
    SAAD, MHF
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 1992, 25 (01) : 49 - 52
  • [6] THE RELATIONSHIP BETWEEN DIET AND THE IMMUNE-RESPONSE OF FISH
    LANDOLT, ML
    AQUACULTURE, 1989, 79 (1-4) : 193 - 206
  • [7] RELATIONSHIP BETWEEN NUTRITIONAL-STATUS AND IMMUNE-RESPONSE IN ACUTE PATIENTS
    PELLUS, AEM
    RUBI, JAG
    ROLDAN, JMR
    BIXQUERT, V
    FRESNEDA, MM
    ALEMAN, MJ
    ALVAREZ, M
    REVISTA CLINICA ESPANOLA, 1983, 169 (04): : 237 - 240
  • [8] RELATIONSHIP BETWEEN IMMUNE-RESPONSE TO HYDRALAZINE AND TO DEOXYRIBONUCLEOPROTEIN IN PATIENTS RECEIVING HYDRALAZINE
    MCDUFFIE, FC
    ARTHRITIS AND RHEUMATISM, 1981, 24 (08): : 1079 - 1081
  • [9] GENETIC-CONTROL OF IMMUNE-RESPONSE - CELLULAR FACTORS
    DAVIS, BK
    SHONNARD, JW
    GILL, TJ
    AMERICAN JOURNAL OF PATHOLOGY, 1976, 82 (02): : A62 - A63
  • [10] HUMORAL AND CELLULAR IMMUNE-RESPONSE IN PSORIASIS
    RUSZCZAK, Z
    CIBORSKA, L
    CZARNECKI, M
    BEDNAROWICZ, G
    ZEITSCHRIFT FUR HAUTKRANKHEITEN H&G, 1986, 61 (06): : 366 - &
12345