Molecular Imaging in Breast Cancer: From Whole-Body PET/CT to Dedicated Breast

被引：38
作者：
Koolen, B. B. [1 ,2 ]
Vogel, W. V. [1 ]
Peeters, M. J. T. F. D. Vrancken [2 ]
Loo, C. E. [3 ]
Rutgers, E. J. Th. [2 ]
Olmos, R. A. Valdes [1 ]
机构：
[1] Antoni Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Nucl Med, Plesmanlaan 121, NL-1066 CX Amsterdam, Netherlands
[2] Antoni Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Surg Oncol, NL-1066 CX Amsterdam, Netherlands
[3] Antoni Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Radiol, NL-1066 CX Amsterdam, Netherlands
来源：
JOURNAL OF ONCOLOGY | 2012年 / 2012卷
关键词：
D O I：
10.1155/2012/438647
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Positron emission tomography (PET), with or without integrated computed tomography (CT), using 18F-fluorodeoxyglucose (FDG) is based on the principle of elevated glucose metabolism in malignant tumors, and its use in breast cancer patients is frequently being investigated. It has been shown useful for classification, staging, and response monitoring, both in primary and recurrent disease. However, because of the partial volume effect and limited resolution of most whole-body PET scanners, sensitivity for the visualization of small tumors is generally low. To improve the detection and quantification of primary breast tumors with FDG PET, several dedicated breast PET devices have been developed. In this nonsystematic review, we shortly summarize the value of whole-body PET/CT in breast cancer and provide an overview of currently available dedicated breast PETs.
引用
收藏
页数：8
相关论文
共 44 条
[21]   PET-Guided Breast Biopsy [J].
Kalinyak, Judith E. ;
Schilling, Kathy ;
Berg, Wendie A. ;
Narayanan, Deepa ;
Mayberry, Jennifer P. ;
Rai, Rajesh ;
DuPree, Elizabeth B. ;
Shusterman, Denise K. ;
Gittleman, Mark A. ;
Luo, Weidong ;
Matthews, Chris G. .
BREAST JOURNAL, 2011, 17 (02) :143-151
[22]   Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: An analysis of 27,825 patient evaluations [J].
Kolb, TM ;
Lichy, J ;
Newhouse, JH .
RADIOLOGY, 2002, 225 (01) :165-175
[23]  
Koolen B. B., Q J NUCL ME IN PRESS
[24]   18F-FDG PET/CT as a staging procedure in primary stage II and III breast cancer: comparison with conventional imaging techniques [J].
Koolen, Bas B. ;
Peeters, Marie-Jeanne T. F. D. Vrancken ;
Aukema, Tjeerd S. ;
Vogel, Wouter V. ;
Oldenburg, Hester S. A. ;
van der Hage, Jos A. ;
Hoefnagel, Cornelis A. ;
Stokkel, Marcel P. M. ;
Loo, Claudette E. ;
Rodenhuis, Sjoerd ;
Rutgers, Emiel J. Th. ;
Olmos, Renato A. Valdes .
BREAST CANCER RESEARCH AND TREATMENT, 2012, 131 (01) :117-126
[25]   Positron emission mammography: Initial clinical results [J].
Levine, EA ;
Freimanis, RI ;
Perrier, ND ;
Morton, K ;
Lesko, NM ;
Bergman, S ;
Geisinger, KR ;
Williams, RC ;
Sharpe, C ;
Zavarzin, V ;
Weinberg, IN ;
Stepanov, PY ;
Beylin, D ;
Lauckner, K ;
Doss, M ;
Lovelace, J ;
Adler, LP .
ANNALS OF SURGICAL ONCOLOGY, 2003, 10 (01) :86-91
[26]   Clinical Imaging Characteristics of the Positron Emission Mammography Camera: PEM Flex Solo II [J].
MacDonald, Lawrence ;
Edwards, John ;
Lewellen, Thomas ;
Haseley, David ;
Rogers, James ;
Kinahan, Paul .
JOURNAL OF NUCLEAR MEDICINE, 2009, 50 (10) :1666-1675
[27]  
Murthy K, 2000, J NUCL MED, V41, P1851
[28]   Comparison of radiation exposure and associated radiation-induced cancer risks from mammography and molecular imaging of the breast [J].
O'Connor, Michael K. ;
Li, Hua ;
Rhodes, Deborah J. ;
Hruska, Carrie B. ;
Clancy, Conor B. ;
Vetter, Richard J. .
MEDICAL PHYSICS, 2010, 37 (12) :6187-6198
[29]   The use of FDG-PET in assessing axillary lymph node status in breast cancer: a systematic review and meta-analysis of the literature [J].
Peare, Rebecca ;
Staff, R. T. ;
Heys, S. D. .
BREAST CANCER RESEARCH AND TREATMENT, 2010, 123 (01) :281-290
[30]   The positron emission mammography/tomography breast imaging and biopsy system (PEM/PET): design, construction and phantom-based measurements [J].
Raylman, Raymond R. ;
Majewski, Stan ;
Smith, Mark F. ;
Proffitt, James ;
Hammond, William ;
Srinivasan, Amarnath ;
McKisson, John ;
Popov, Vladimir ;
Weisenberger, Andrew ;
Judy, Clifford O. ;
Kross, Brian ;
Ramasubramanian, Srikanth ;
Banta, Larry E. ;
Kinahan, Paul E. ;
Champley, Kyle .
PHYSICS IN MEDICINE AND BIOLOGY, 2008, 53 (03) :637-653
12345