Molecular Imaging in Breast Cancer: From Whole-Body PET/CT to Dedicated Breast

被引：38
作者：
Koolen, B. B. [1 ,2 ]
Vogel, W. V. [1 ]
Peeters, M. J. T. F. D. Vrancken [2 ]
Loo, C. E. [3 ]
Rutgers, E. J. Th. [2 ]
Olmos, R. A. Valdes [1 ]
机构：
[1] Antoni Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Nucl Med, Plesmanlaan 121, NL-1066 CX Amsterdam, Netherlands
[2] Antoni Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Surg Oncol, NL-1066 CX Amsterdam, Netherlands
[3] Antoni Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Radiol, NL-1066 CX Amsterdam, Netherlands
来源：
JOURNAL OF ONCOLOGY | 2012年 / 2012卷
关键词：
D O I：
10.1155/2012/438647
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Positron emission tomography (PET), with or without integrated computed tomography (CT), using 18F-fluorodeoxyglucose (FDG) is based on the principle of elevated glucose metabolism in malignant tumors, and its use in breast cancer patients is frequently being investigated. It has been shown useful for classification, staging, and response monitoring, both in primary and recurrent disease. However, because of the partial volume effect and limited resolution of most whole-body PET scanners, sensitivity for the visualization of small tumors is generally low. To improve the detection and quantification of primary breast tumors with FDG PET, several dedicated breast PET devices have been developed. In this nonsystematic review, we shortly summarize the value of whole-body PET/CT in breast cancer and provide an overview of currently available dedicated breast PETs.
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页数：8
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