Hepatitis C Virus Infection in Patients with Hemophilia in Isfahan, Iran

被引:0
作者
Yazdani, Mohammad Reza [1 ]
Kassaian, Nazila [1 ]
Ataei, Behrooz [1 ]
Nokhodian, Zary [1 ]
Adibi, Peyman [2 ]
机构
[1] Isfahan Univ Med Sci, Infect Dis & Trop Med Res Ctr, Esfahan, Iran
[2] Isfahan Univ Med Sci, Dept Gastroenterol, Integrat Funct Gastroenterol Res Ctr, Esfahan, Iran
关键词
Hemophilia; hepatitis C; risk factors;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: Patients with hereditary bleeding disorders are at risk of viral infection such as hepatitis C due to frequent transfusion of blood and blood products. This study aimed to determine the prevalence of hepatitis C and associated risk factors in hemophilic patients in Isfahan, the second big province in Iran. Methods: In a descriptive study, patients with hemophilia in Isfahan province were enrolled. A questionnaire, including demographic and risk factors of hepatitis C was completed through a structured interview with closed questions by a trained interviewer for each patient and HCV-Ab test results were extracted from patient records. Results: In this study, 232 of 350 patients with hemophilia A and B (66%) were positive for hepatitis C. Based on Multivariate Logistic Regression model, no independent risk factor was found. Conclusions: Prevalence of hepatitis C in patients with haemophilia A and B in Isfahan is high. Since no independent risk factor for hepatitis C disease was found in this high risk group, it can be concluded that multitransfusion is the only predictor for hepatitis C.
引用
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页码:S89 / S93
页数:5
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