CHARACTERIZATION OF THE (6-4) PHOTOPRODUCT OF 2'-DEOXYCYTIDYLYL-(3'-GREATER-THAN-5')-THYMIDINE AND OF ITS DEWAR VALENCE ISOMER

被引：25

作者：

DOUKI, T ^{[1
]}

VOITURIEZ, L ^{[1
]}

CADET, J ^{[1
]}

机构：

[1] CEN,DEPT RECH FONDAMENTALE,CHIM LABS,85X,F-38041 GRENOBLE,FRANCE

来源：

PHOTOCHEMISTRY AND PHOTOBIOLOGY | 1991年 / 53卷 / 03期

关键词：

D O I：

10.1111/j.1751-1097.1991.tb03631.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Far-UV irradiation of dCpT in aqueous solution was found to generate the corresponding pyrimidine (6-4) pyrimidone photoadduct and the related Dewar valence isomer. The two photoproducts of dCpT were found to undergo deamination in aqueous solution, giving rise to the corresponding dUpT derivatives at a relatively slow rate. It was also shown that the Dewar isomer is much more alkali-labile than its (6-4) precursor.

引用

页码：293 / 297

页数：5

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