Total synthesis of angucyclines .5. Synthesis of (+-)-rubiginone B2 by intra-molecular nucleophilic displacement of an anthraquinone precursor

被引：0
|
作者：
Krohn, K
Droge, W
Hintze, F
机构：
来源：
ANALES DE QUIMICA | 1995年 / 91卷 / 5-6期
关键词：
rubiginone; nucleophilic displacement;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Intramolecular nucleophilic displacement reaction of the ketoester 2 yields the angularly condensed system 7. Its conversion to the racemic angucycline antibiotic rubiginone B-2 (1a) is achieved by ethoxydecarbonylation to 8, deoxygenation via the thioketal 9 and photooxygenation.
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页码：388 / 393
页数：6
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