Total synthesis of angucyclines .5. Synthesis of (+-)-rubiginone B2 by intra-molecular nucleophilic displacement of an anthraquinone precursor

被引：0

作者：

Krohn, K

Droge, W

Hintze, F

机构：

来源：

ANALES DE QUIMICA | 1995年 / 91卷 / 5-6期

关键词：

rubiginone; nucleophilic displacement;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Intramolecular nucleophilic displacement reaction of the ketoester 2 yields the angularly condensed system 7. Its conversion to the racemic angucycline antibiotic rubiginone B-2 (1a) is achieved by ethoxydecarbonylation to 8, deoxygenation via the thioketal 9 and photooxygenation.

引用

页码：388 / 393

页数：6

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