ANALYTICAL QUALITY-CONTROL IN NEONATAL SCREENING

被引：2

作者：

TUUMINEN, T ^{[1
]}

KAPYAHO, K ^{[1
]}

RAKKOLAINEN, A ^{[1
]}

WEBER, T ^{[1
]}

机构：

[1] AURORA CITY HOSP,HELSINKI,FINLAND

来源：

CLINICAL BIOCHEMISTRY | 1994年 / 27卷 / 06期

关键词：

QUALITY CONTROL; STANDARDIZATION; PRECISION; ACCURACY; CLINICAL GOALS; NEONATAL SCREENING;

D O I：

10.1016/0009-9120(94)00054-Y

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

This critical review questions the present understanding in monitoring of analytical quality control in neonatal screening. Current status and historical background of the analytical quality control, particularly of the tests intended for the screening of congenital hypothyroidism and some inborn errors of metabolism, is reviewed. The reasons why attempts to standardize immunoassays through the preparation of a so-called ''gold standard'' (e.g. for thyrotropin) will not resolve noncomparability of results are discussed. The review presents arguments for the necessity of elaboration of international guidelines for methods assessment and comparison with an emphasis on their clinical relevance.

引用

页码：429 / 434

页数：6