BROMOCRIPTINE THERAPY IN 3 PATIENTS WITH PROLACTIN SECRETING PITUITARY-ADENOMAS

被引:0
|
作者
SAPUNAR, J [1 ]
LOPEZ, JM [1 ]
HUETE, I [1 ]
TAGLE, R [1 ]
机构
[1] CATHOLIC UNIV CHILE,HOSP CLIN,DEPT RADIOL,SANTIAGO,CHILE
关键词
PITUITARY NEOPLASMS; ADENOMA; PROLACTIN; BROMOCRIPTINE; PROGNOSIS;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Bromocriptine was used to treat 3 patients with prolactin secreting pituitary adenoma. Diagnosis was based on the presence of a sellar tumor over 1 cm in size at CT scanning and a serum prolactin concentration above 150 ng/ml. All patients were symptomatic from pituitary hypofunction or from tumor compression of neighboring areas. Bromocriptine was given at increasing doses up to 10 mg/day. Prolactine reached normal levels 1 to 7 months later. Tumor reduction was confirmed by high resolution scanning. The mechanism of bromocriptine effect on these tumors is discussed.
引用
收藏
页码:168 / 173
页数:6
相关论文
共 50 条
  • [31] Long-term treatment with bromocriptine of a plurihormonal pituitary adenoma secreting thyrotropin, growth hormone and prolactin
    Shimatsu, A
    Murabe, H
    Nakamura, Y
    Mizuta, H
    Ihara, C
    Nakao, K
    ENDOCRINE JOURNAL, 1999, 46 (01) : 159 - 165
  • [32] Temozolomide therapy in a man with an aggressive prolactin-secreting pituitary neoplasm: morphological findings
    Kovacs, Kalman
    Horvath, Eva
    Syro, Luis V.
    Uribe, Humberto
    Penagos, Luis C.
    Ortiz, Leon D.
    Fadul, Camilo E.
    HUMAN PATHOLOGY, 2007, 38 (01) : 185 - 189
  • [33] Pharmacogenetics of D2 dopamine receptor gene in prolactin-secreting pituitary adenomas
    Filopanti, M.
    Lania, A. G.
    Spada, A.
    EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2010, 6 (01) : 43 - 53
  • [34] THE PLACE OF SURGERY IN THE MANAGEMENT OF PROLACTIN SECRETING ADENOMAS
    Rotariu, D. I.
    Costachescu, B.
    Ungureanu, M. C.
    Eva, L.
    Leustean, L.
    Preda, C.
    Cristea, C.
    Iliescu, B. F.
    ACTA ENDOCRINOLOGICA-BUCHAREST, 2024, 20 (01) : 65 - 73
  • [35] USE OF ATHYMIC NUDE-MICE FOR INVIVO STUDIES OF HUMAN GROWTH-HORMONE-SECRETING PITUITARY-ADENOMAS
    PUCHNER, MJA
    LUDECKE, DK
    SAEGER, W
    HERRMANN, HD
    HORMONE RESEARCH, 1991, 35 (05) : 198 - 204
  • [36] Long term toxicity and prognostic factors of radiation therapy for secreting and non-secreting pituitary adenomas
    Rieken, Stefan
    Habermehl, Daniel
    Welzel, Thomas
    Mohr, Angela
    Lindel, Katja
    Debus, Juergen
    Combs, Stephanie E.
    RADIATION ONCOLOGY, 2013, 8
  • [37] Long term toxicity and prognostic factors of radiation therapy for secreting and non-secreting pituitary adenomas
    Stefan Rieken
    Daniel Habermehl
    Thomas Welzel
    Angela Mohr
    Katja Lindel
    Jürgen Debus
    Stephanie E Combs
    Radiation Oncology, 8
  • [38] Prolactin-secreting pituitary adenomas: male-specific differences in pathogenesis, clinical presentation and treatment
    Dzialach, Lukasz
    Sobolewska, Joanna
    Zak, Zuzanna
    Respondek, Wioleta
    Witek, Przemyslaw
    FRONTIERS IN ENDOCRINOLOGY, 2024, 15
  • [39] The risks of overlooking the diagnosis of secreting pituitary adenomas
    Thierry Brue
    Frederic Castinetti
    Orphanet Journal of Rare Diseases, 11
  • [40] The risks of overlooking the diagnosis of secreting pituitary adenomas
    Brue, Thierry
    Castinetti, Frederic
    ORPHANET JOURNAL OF RARE DISEASES, 2016, 11 : 1 - 17