ENHANCEMENT OF ALCOHOL WITHDRAWAL CONVULSIONS IN MICE BY HALOPERIDOL

被引：26

作者：

BLUM, K

EUBANKS, JD

WALLACE, JE

HAMILTON, H

机构：

[1] UNIV TEXAS, CTR HLTH SCI, DEPT PATHOL, DIV DRUG & ALCOHOL ABUSE, SAN ANTONIO, TX 78229 USA

[2] UNIV TEXAS, CTR HLTH SCI, DEPT PHARMACOL, DIV DRUG & ALCOHOL ABUSE, SAN ANTONIO, TX 78229 USA

来源：

CLINICAL TOXICOLOGY | 1976年 / 9卷 / 03期

关键词：

D O I：

10.3109/15563657608988141

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

Although haloperidol has been used with a certain degree of success for treatment of acute alcohol abstinence, widespread use of haloperidol for treatment of alcohol withdrawal is cautioned against. In experimentally induced ethanol withdrawal, chlordiazepoxide appears to be a more effective and safer agent for ameliorating symptoms associated with excitation such as tremor, insomnia, anxiety and hyperexcitability. A double blind comparative clinical investigation between chlordiazepoxide and haloperidol for treatment of alcohol withdrawal is warranted.

引用

页码：427 / 434

页数：8

共 18 条

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