STRUCTURE-ACTIVITY-RELATIONSHIPS OF 6-(HETEROCYCLYL)-METHYLENE PENAM SULFONES - A NEW CLASS OF BETA-LACTAMASE INHIBITORS

被引：32

作者：

CHEN, YPL ^{[1
]}

CHANG, CW ^{[1
]}

HEDBERG, K ^{[1
]}

GUARINO, K ^{[1
]}

WELCH, WM ^{[1
]}

KIESSLING, L ^{[1
]}

RETSEMA, JA ^{[1
]}

HASKELL, SL ^{[1
]}

ANDERSON, M ^{[1
]}

MANOUSOS, M ^{[1
]}

BARRETT, JF ^{[1
]}

机构：

[1] PFIZER INC,CENT RES,DEPT IMMUNOL & INFECT DIS,GROTON,CT 06340

来源：

JOURNAL OF ANTIBIOTICS | 1987年 / 40卷 / 06期

关键词：

D O I：

10.7164/antibiotics.40.803

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：803 / 822

页数：20

共 17 条

[1]

AIMETTI JA, 1979, TETRAHEDRON LETT, P4631

[2] 6-ACETYLMETHYLENEPENICILLANIC ACID (RO 15-1903), A POTENT BETA-LACTAMASE INHIBITOR .2. ANTIBACTERIAL PROPERTIES [J].

ANGEHRN, P ;

ARISAWA, M .

JOURNAL OF ANTIBIOTICS, 1982, 35 (11) :1584-1589

[3] 6-ACETYLMETHYLENEPENICILLANIC ACID (RO 15-1903), A POTENT BETA-LACTAMASE INHIBITOR .1. INHIBITION OF CHROMOSOMALLY AND R-FACTOR-MEDIATED BETA-LACTAMASES [J].

ARISAWA, M ;

THEN, RL .

JOURNAL OF ANTIBIOTICS, 1982, 35 (11) :1578-1583

[4] SYNTHESIS OF A POTENT BETA-LACTAMASE INHIBITOR-1,1-DIOXO-6-(2-PYRIDYL)METHYLENEPENICILLANIC ACID AND ITS REACTION WITH SODIUM METHOXIDE [J].

CHEN, YL ;

CHANG, CW ;

HEDBERG, K .

TETRAHEDRON LETTERS, 1986, 27 (30) :3449-3452

[5]

CHEN YL, 1985, Patent No. 150984

[6] CP-45,899, A BETA-LACTAMASE INHIBITOR THAT EXTENDS ANTIBACTERIAL SPECTRUM OF BETA-LACTAMS - INITIAL BACTERIOLOGICAL CHARACTERIZATION [J].

ENGLISH, AR ;

RETSEMA, JA ;

GIRARD, AE ;

LYNCH, JE ;

BARTH, WE .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1978, 14 (03) :414-419

[7]

ERICSSON HM, 1971, ACTA PATHOL MICROB B, V217, P64

[8]

HOWARTH TT, 1976, J CHEM SOC CHEM COMM, P266

[9] HOMOGENEOUS, PALLADIUM(0)-CATALYZED EXCHANGE DEPROTECTION OF ALLYLIC ESTERS, CARBONATES, AND CARBAMATES [J].

JEFFREY, PD ;

MCCOMBIE, SW .

JOURNAL OF ORGANIC CHEMISTRY, 1982, 47 (03) :587-590

[10]

MOORE BS, 1980, Patent No. 2045755

← 1 2 →