HORMONAL EFFECTS OF THORACIC EXTRADURAL ANALGESIA FOR CARDIAC-SURGERY

被引：100

作者：

MOORE, CM ^{[1
]}

CROSS, MH ^{[1
]}

DESBOROUGH, JP ^{[1
]}

BURRIN, JM ^{[1
]}

MACDONALD, IA ^{[1
]}

HALL, GM ^{[1
]}

机构：

[1] HAMMERSMITH HOSP, ROYAL POSTGRAD MED SCH, DEPT ANAESTHET, LONDON W12 0HS, ENGLAND

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1995年 / 75卷 / 04期

关键词：

ANALGESIC TECHNIQUES; EXTRADURAL; HORMONES; CORTICOSTEROID; SYMPATHETIC NERVOUS SYSTEM; CATECHOLAMINES; SURGERY; CARDIOVASCULAR; HEART; CARDIOPULMONARY BYPASS;

D O I：

10.1093/bja/75.4.387

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We have investigated the hormonal and metabolic effects of thoracic extradural analgesia with bupivacaine in addition to sufentanil 20 mu g kg(-1) in nine patients undergoing coronary artery bypass surgery. A control group received general anaesthesia alone. The catecholamine response was inhibited for 24 h after surgery in patients who had received extradural analgesia, and the cortisol response was suppressed during cardiopulmonary bypass. Blood glucose values were unchanged until 24 h after surgery in the extradural group. There were no significant differences in cardiac index between the two groups of patients, although heart rate and mean arterial pressure decreased before surgery in patients who received extradural analgesia. The benefits of this technique in terms of a reduction in postoperative morbidity remain to be determined.

引用

页码：387 / 393

页数：7

共 20 条

[1] BILATERAL UPPER THORACIC SYMPATHECTOMY IN ANGINA PECTORIS - RESULTS IN 52 CASES [J].

BIRKETT, DA ;

APTHORP, GH ;

CHAMBERLAIN, DA ;

HAYWARD, GW ;

TUCKWELL, EG .

BMJ-BRITISH MEDICAL JOURNAL, 1965, 2 (5455) :187-+

[2] EFFECTS OF THORACIC EPIDURAL-ANESTHESIA ON CORONARY-ARTERIES AND ARTERIOLES IN PATIENTS WITH CORONARY-ARTERY DISEASE [J].

BLOMBERG, S ;

EMANUELSSON, H ;

KVIST, H ;

LAMM, C ;

PONTEN, J ;

WAAGSTEIN, F ;

RICKSTEN, SE .

ANESTHESIOLOGY, 1990, 73 (05) :840-847

[3]

BLOMBERG S, 1989, ANESTH ANALG, V69, P558

[4]

Boden G, 1967, Diabetologia, V3, P413, DOI 10.1007/BF01228076

[5]

BROMAGE PR, 1971, SURG GYNECOL OBSTETR, V132, P1051

[6] HORMONAL RESPONSES TO CARDIAC-SURGERY - EFFECTS OF SUFENTANIL, SOMATOSTATIN AND GANGLION BLOCK [J].

DESBOROUGH, JP ;

HALL, GM ;

HART, GR ;

BURRIN, JM ;

BLOOM, SR .

BRITISH JOURNAL OF ANAESTHESIA, 1990, 64 (06) :688-695

[7] BLOCKING EFFECT OF EPIDURAL ANALGESIA ON ADRENOCORTICAL AND HYPERGLYCEMIC RESPONSES TO SURGERY [J].

ENGQUIST, A ;

BRANDT, MR ;

FERNANDES, A ;

KEHLET, H .

ACTA ANAESTHESIOLOGICA SCANDINAVICA, 1977, 21 (04) :330-335

[8]

HALL GM, 1978, ANAESTHESIA, V33, P924

[9]

Joachimsson P O, 1989, J Cardiothorac Anesth, V3, P444, DOI 10.1016/S0888-6296(89)97603-5

[10] SURGICAL STRESS - THE ROLE OF PAIN AND ANALGESIA [J].

KEHLET, H .

BRITISH JOURNAL OF ANAESTHESIA, 1989, 63 (02) :189-195

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