EPIDERMAL GROWTH-FACTOR IN TOPICAL TREATMENT FOLLOWING EPIKERATOPLASTY

被引：12

作者：

CAPOROSSI, A ^{[1
]}

MANETTI, C ^{[1
]}

机构：

[1] UNIV SIENA, NUOVO POLICLIN LE SCOTTE, IST SCI OFTALMOL, I-53100 SIENA, ITALY

来源：

OPHTHALMOLOGICA | 1992年 / 205卷 / 03期

关键词：

EPIDERMAL GROWTH FACTOR; EPIKERATOPLASTY; CORNEAL HEALING; CORNEAL EPITHELIUM;

D O I：

10.1159/000310325

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The efficacy of epidermal growth factor (EGF) in reducing the healing time of the cornea after an epikeratoplasty has been evaluated in an open study in two groups of patients. The time required for complete reepithelialization of the cornea was recorded, and the data obtained were analyzed statistically. In the EGF group the reepithelialization was significantly faster than in the control group. These results indicate that EGF is effective in reducing the reepithelialization time of the cornea after an epikeratoplasty.

引用

页码：121 / 124

页数：4

共 21 条

[1]

BINDER PS, 1987, ARCH OPHTHALMOL-CHIC, V105, P63

[2]

Cohen S, 1974, Recent Prog Horm Res, V30, P551

[3]

COHEN S, 1962, J BIOL CHEM, V237, P1555

[4] EFFECT OF THE EPIDERMAL GROWTH-FACTOR (EGF) ON THE CORNEAL EPITHELIUM IN HUMANS [J].

DANIELE, S ;

FRATI, L ;

FIORE, C ;

SANTONI, G .

ALBRECHT VON GRAEFES ARCHIV FUR KLINISCHE UND EXPERIMENTELLE OPHTHALMOLOGIE, 1979, 210 (03) :159-165

[5]

FABRICANT R, 1982, ARCH OPHTHALMOL-CHIC, V100, P994

[6]

FABRICANT RN, 1980, EFFECTS EPIDERMAL GR

[7]

Feldman S T, 1991, Refract Corneal Surg, V7, P232

[8]

FRANGIEH GT, 1988, OPHTHALMOLOGY, V95, P213

[9] EFFECTS OF EPIDERMAL AND FIBROBLAST GROWTH-FACTORS ON THE REPAIR OF CORNEAL ENDOTHELIAL WOUNDS IN BOVINE CORNEAS MAINTAINED IN ORGAN-CULTURE [J].

GOSPODAROWICZ, D ;

GREENBURG, G .

EXPERIMENTAL EYE RESEARCH, 1979, 28 (02) :147-157

[10] GROWTH-FACTORS IN MAMMALIAN-CELL CULTURE [J].

GOSPODAROWICZ, D ;

MORAN, JS .

ANNUAL REVIEW OF BIOCHEMISTRY, 1976, 45 :531-558

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