FC-EPSILON-RI ON HUMAN LANGERHANS CELLS - A RECEPTOR IN SEARCH OF NEW FUNCTIONS

被引：55

作者：

BIEBER, T

机构：

来源：

IMMUNOLOGY TODAY | 1994年 / 15卷 / 02期

关键词：

D O I：

10.1016/0167-5699(94)90132-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The recent demonstration that the high-affinity receptor for IgE, FcepsilonRI, is expressed on human Langerhans cells casts a new perspective on the function of this receptor. This observation also provides a new direction for further investigation into the pathophysiological relevance of Langerhans cells and other antigen-presenting cells in the development of atopic diseases.

引用

收藏

页码：52 / 53

页数：2

相关论文

共 16 条

[1]

ALBER G, 1991, J BIOL CHEM, V266, P22613

[2] SIGNAL-TRANSDUCTION BY FC-RECEPTORS - THE FC-EPSILON-RI CASE [J].

BEAVEN, MA ;

METZGER, H .

IMMUNOLOGY TODAY, 1993, 14 (05) :222-226

[3] PROTEIN-TYROSINE PHOSPHORYLATION - AN ESSENTIAL COMPONENT OF FC-EPSILON-RI SIGNALING [J].

BENHAMOU, M ;

SIRAGANIAN, RP .

IMMUNOLOGY TODAY, 1992, 13 (06) :195-197

[4] OCCURRENCE OF IGE-BEARING EPIDERMAL LANGERHANS CELLS IN ATOPIC ECZEMA - A STUDY OF THE TIME COURSE OF THE LESIONS AND WITH REGARD TO THE IGE SERUM LEVEL [J].

BIEBER, T ;

DANNENBERG, B ;

PRINZ, JC ;

RIEBER, EP ;

STOLZ, W ;

BRAUNFALCO, O ;

RING, J .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1989, 93 (02) :215-219

[5] INDUCTION OF FC-EPSILON-R2/CD23 ON HUMAN EPIDERMAL LANGERHANS CELLS BY HUMAN RECOMBINANT INTERLEUKIN-4 AND GAMMA-INTERFERON [J].

BIEBER, T ;

RIEGER, A ;

NEUCHRIST, C ;

PRINZ, JC ;

RIEBER, EP ;

BOLTZNITULESCU, G ;

SCHEINER, O ;

KRAFT, D ;

RING, J ;

STINGL, G .

JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 170 (01) :309-314

[6] HUMAN EPIDERMAL LANGERHANS CELLS EXPRESS THE HIGH-AFFINITY RECEPTOR FOR IMMUNOGLOBULIN-E (FC-EPSILON-RI) [J].

BIEBER, T ;

DELASALLE, H ;

WOLLENBERG, A ;

HAKIMI, J ;

CHIZZONITE, R ;

RING, J ;

HANAU, D ;

DELASALLE, C .

JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 175 (05) :1285-1290

[7] INVIVO MODULATION OF THE HIGH-AFFINITY RECEPTOR FOR IGE (FC-EPSILON-RI) ON HUMAN EPIDERMAL LANGERHANS CELLS [J].

BIEBER, T ;

RING, J .

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 1992, 99 (2-4) :204-207

[8]

Bieber Thomas, 1993, Journal of Investigative Dermatology, V101, P411

[9] THE PRESENCE OF IGE MOLECULES ON EPIDERMAL LANGERHANS CELLS IN PATIENTS WITH ATOPIC-DERMATITIS [J].

BRUYNZEELKOOMEN, C ;

VANWICHEN, DF ;

TOONSTRA, J ;

BERRENS, L ;

BRUYNZEEL, PLB .

ARCHIVES OF DERMATOLOGICAL RESEARCH, 1986, 278 (03) :199-205

[10] EPSILON-BP, A BETA-GALACTOSIDE-BINDING ANIMAL LECTIN, RECOGNIZES IGE RECEPTOR (FC-EPSILON-RI) AND ACTIVATES MAST-CELLS [J].

FRIGERI, LG ;

ZUBERI, RI ;

LIU, FT .

BIOCHEMISTRY, 1993, 32 (30) :7644-7649