THE EFFECT OF CARBON-DIOXIDE ON THE DIAMETER OF BRAIN CAPILLARIES

被引:78
作者
ATKINSON, JLD
ANDERSON, RE
SUNDT, TM
机构
[1] Mayo Clinic, Department of Neurosurgery, Rochester
关键词
Capillary recruitment; Capillary vasomotion; Carbon black; Microcirculation; Perfusion fixation;
D O I
10.1016/0006-8993(90)91046-J
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Cerebral capillaries in cats subjected to variations in carbon dioxide tensions were studied using carbon black perfusion fixation. Five animals each were grouped into hypocapnia, normocapnia, and hypercapnia and 500 cortical, 250 white matter and 250 caudate nucleus capillaries per group were analyzed at 400 × magnification. Capillary diameters were found to change significantly in the cortex (6.1-10.0 μm), white matter (6.5-9.6 μm) and caudate nucleus (6.3-8.8 μm) from hypocapnia to hypercapnia, respectively. These findings suggest that capillary vasomotion occurs and that capillaries are not rigid tubes as previously portrayed. © 1990.
引用
收藏
页码:333 / 340
页数:8
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