SOME DEVELOPMENTS IN THE PHOSPHITE TRIESTER METHOD FOR SYNTHESIS OF OLIGONUCLEOTIDES

被引：58
作者：
LETSINGER, RL
GROODY, EP
LANDER, N
TANAKA, T
机构：
来源：
TETRAHEDRON | 1984年 / 40卷 / 01期
关键词：
D O I：
10.1016/0040-4020(84)85112-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
引用
收藏
页码：137 / 143
页数：7
相关论文
共 28 条
[1]   NUCLEOSIDE 3'-PHOSPHOTRIESTERS AS KEY INTERMEDIATES FOR OLIGORIBONUCLEOTIDE SYNTHESIS .4. NEW METHOD FOR REMOVAL OF 2,2,2-TRICHLOROETHYL GROUP AND P-31-NMR AS A NEW TOOL FOR ANALYSIS OF DEBLOCKING OF INTERNUCLEOTIDE PHOSPHATE PROTECTING GROUPS [J].
ADAMIAK, RW ;
BIALA, E ;
GRZESKOWIAK, K ;
KIERZEK, R ;
KRASZEWSKI, A ;
MARKIEWICZ, WT ;
STAWINSKI, J ;
WIEWIOROWSKI, M .
NUCLEIC ACIDS RESEARCH, 1977, 4 (07) :2321-2329
[2]   DEOXYNUCLEOSIDE PHOSPHORAMIDITES - A NEW CLASS OF KEY INTERMEDIATES FOR DEOXYPOLYNUCLEOTIDE SYNTHESIS [J].
BEAUCAGE, SL ;
CARUTHERS, MH .
TETRAHEDRON LETTERS, 1981, 22 (20) :1859-1862
[3]   SYNTHESIS OF OLIGORIBONUCLEOTIDES BASED ON FACILE CLEAVAGE OF METHYL PHOSPHOTRIESTER INTERMEDIATES [J].
DAUB, GW ;
VANTAMELEN, EE .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (10) :3526-3528
[4]  
DENSHOWITZ S, 1961, J ORG CHEM, V26, P3595
[5]   FRAGMENTATIONS WITH SUPERNUCLEOPHILES .7. 2,2,2-TRICHLORO-TERT-BUTYLOXYCARBONYL GROUP (TCBOC) - ACID-RESISTANT AND BASE-RESISTANT PROTECTING GROUP REMOVABLE UNDER MILD CONDITIONS [J].
ECKERT, H ;
LISTL, M ;
UGI, I .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1978, 17 (05) :361-362
[6]   OLIGONUCLEOTIDE SYNTHESES BY MEANS OF 2,2,2-TRICHLOROETHYL PHOSPHORODICHORIDATE [J].
ECKSTEIN, F ;
RIZK, I .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1967, 6 (11) :949-&
[7]   SYNTHESIF OF OLIGONUCLEOTIDES BY USE OF PHOSPHORIC TRIESTERS [J].
ECKSTEIN, F ;
RIZK, I .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1967, 6 (08) :695-&
[8]  
FINNAN JL, 1980, NUCL ACIDS RES S SER, V7, P133
[9]  
GERRARD W, 1949, Research, V2, P536
[10]   (2-TRICHLOROMETHYL-2-PROPYL)-CHLOROPHOSPHATES AS PHOSPHORYLATING REAGENTS [J].
KELLNER, HA ;
UGI, I .
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 1979, 34 (08) :1159-1161
123