A rare case of hyperoxaluria presenting with acute liver injury and stone-free kidney injury

被引：5

作者：

Kim, Si-eun ^{[1
]}

Kim, Seon-Jae ^{[1
]}

Chu, Seong Taek ^{[1
]}

Yang, Seung Hee ^{[2
]}

Kim, Yon Su ^{[3
]}

Cha, Ran-hui ^{[4
]}

机构：

[1] Natl Med Ctr, Dept Internal Med, Seoul, South Korea

[2] Seoul Natl Univ, Coll Med, Kidney Res Inst, Seoul, South Korea

[3] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[4] Natl Med Ctr, Dept Internal Med, Div Nephrol, 245 Eulji Ro, Seoul 100799, South Korea

来源：

KIDNEY RESEARCH AND CLINICAL PRACTICE | 2015年 / 34卷 / 02期

关键词：

Acute kidney injury; Acute liver injury; Oxalate nephropathy;

D O I：

10.1016/j.krcp.2014.09.006

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A 49-year-old woman visited the clinic because of acute hepatitis and acute kidney injury with decreased urine output presenting microscopic hematuria and proteinuria. An abdominal computed tomography revealed a localized, hypoattenuatecl lesion in a hepatic lateral segment, and kidney biopsy showed oxalate crystal deposition with tubular necrosis. In addition, the patient's 24-hour urinary excretion of oxalate was increased. Her kidney and liver injury improved after sessions of hemodialysis, and urinary oxalate excretion was normalized. Major mutations in primary hyperoxaluria have not been proven. A full sequencing of target genes may be helpful to diagnose a rare form of primary hyperoxaluria. Copyright (C) 2015. The Korean Society of Nephrology. Published by Elsevier.

引用

页码：113 / 116

页数：4

共 15 条

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