MULTIPLE-SCATTERING IN OPTICAL COHERENCE MICROSCOPY

被引:123
作者
YADLOWSKY, MJ [1 ]
SCHMITT, JM [1 ]
BONNER, RF [1 ]
机构
[1] NIH,BIOMED ENGN & INSTRUMENTAT PROGRAM,BETHESDA,MD 20892
来源
APPLIED OPTICS | 1995年 / 34卷 / 25期
关键词
D O I
10.1364/AO.34.005699
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We show that the multiple-scatter rejection provided by optical coherence microscopy (low-coherence interferometry) can be incomplete in optically turbid media and that multiple scattering manifests itself in two distinct ways. Multiple small-angle scattering results in an effective probe field that is stronger than expected from a first-order beam extinction model, but that contains a distorted wave front that enhances the apparent reflectance of small structures relative to those that are larger than the unscattered incident beam. Multiple wide-angle scattering produces a broad diffuse haze that reduces the contrast of subsequent features.
引用
收藏
页码:5699 / 5707
页数:9
相关论文
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  • [1] Huang D., Wand J., Lin C.P., Puliafito C.A., Fujimoto J.G., Micron-resolution ranging of cornea anterior chamber by optical reflectometry, Lasers Surg. Med, 11, pp. 419-425, (1991)
  • [2] Huang D., Swanson E.A., Lin C.P., Schuman J.S., Stinson W.G., Chang W., Hee M.R., Flotte T., Gregory K., Puliafito C.A., Fujimoto J.G., Optical coherence tomography, Science, 254, pp. 1178-1181, (1991)
  • [3] Hitzenberger C.K., Measurement of corneal thickness by low-coherence interferometry, Appl. Opt, 31, pp. 6637-6642, (1992)
  • [4] Swanson E.A., Izatt J.A., Hee M.R., Huang D., Lin C.P., Schuman J.S., Puliafito C.A., Fujimoto J.G., In vivo retinal imaging by optical coherence tomography, Opt. Lett, 17, pp. 151-153, (1992)
  • [5] Schmitt J.M., Knuttel A., Bonner R.F., Measurement of optical properties of biological tissues by low-coherence reflectometry, Appl. Opt, 32, pp. 6032-6042, (1993)
  • [6] Schmitt J.M., Knuttel A., Gandjbakhche A., Bonner R.F., Optical characterization of dense tissues using low-coherence interferometry, Holography, Interferometry, and Optical Pattern Recognition in Biomedicine III, 1889, pp. 197-210, (1993)
  • [7] Schmitt J.M., Knuttel A., Yadlowsky M., Eckhaus M.A., Optical-coherence tomography of a dense tissue: Statistics of attenuation and backscattering, Phys. Med. Biol, 39, pp. 1705-1720, (1994)
  • [8] Izatt J.A., Hee M.R., Owen G.M., Swanson E.A., Fujimoto J.G., Optical coherence microscopy in scattering media, Opt. Lett, 19, pp. 590-592, (1994)
  • [9] Sonnenschein C.M., Horrigan F.A., Signal-to-noise relationships for coaxial systems that heterodyne backscatter from the atmosphere, Appl. Opt, 10, pp. 1600-1604, (1971)
  • [10] Schmitt J.M., Yadlowsky M.J., Bonner R.F., Subsurface imaging of living skin with optical coherence microscopy, Dermatology