TESTOSTERONE AND RISK-FACTORS FOR CARDIOVASCULAR-DISEASE IN MEN

被引：0
作者：
BARRETTCONNOR, EL
机构：
来源：
DIABETES & METABOLISM | 1995年 / 21卷 / 03期
关键词：
CORONARY HEART DISEASE; HDL-CHOLESTEROL; MEN; TESTOSTERONE;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
It has been assumed for years that male testosterone levels play a central role in worsening lipoprotein patterns and causing greater susceptibility to ischemic heart disease. Yet most clinical trials of quasi-physiologic doses of intramuscular testosterone in older men show no effect on high-density lipoprotein (HDL)-cholesterol, while cross-sectional epidemiologic studies almost uniformly find that endogenous testosterone levels are positively associated with HDL-cholesterol levels. Further work is required to determine whether and why physiologic testosterone levels in the high normal range appear to be conducive to optimal cardiovascular health for adult men.
引用
收藏
页码：156 / 161
页数：6
相关论文
共 42 条
[1]   RELATIONSHIPS BETWEEN PLASMA-LIPOPROTEIN CONCENTRATIONS AND INSULIN ACTION IN AN OBESE HYPERINSULINEMIC POPULATION [J].
ABBOTT, WGH ;
LILLIOJA, S ;
YOUNG, AA ;
ZAWADZKI, JK ;
YKIJARVINEN, H ;
CHRISTIN, L ;
HOWARD, BV .
DIABETES, 1987, 36 (08) :897-904
[2]   TESTOSTERONE CONCENTRATIONS IN WOMEN AND MEN WITH NIDDM [J].
ANDERSSON, B ;
VERMEULEN, A ;
MARIN, P ;
BJORNTORP, P ;
LISSNER, L .
DIABETES CARE, 1994, 17 (05) :405-411
[3]   PHYSIOLOGICAL TESTOSTERONE LEVELS IN NORMAL MEN SUPPRESS HIGH-DENSITY-LIPOPROTEIN CHOLESTEROL LEVELS [J].
BAGATELL, CJ ;
KNOPP, RH ;
VALE, WW ;
RIVIER, JE ;
BREMNER, WJ .
ANNALS OF INTERNAL MEDICINE, 1992, 116 (12) :967-973
[4]   METABOLIC AND BEHAVIORAL-EFFECTS OF HIGH-DOSE, EXOGENOUS TESTOSTERONE IN HEALTHY-MEN [J].
BAGATELL, CJ ;
HEIMAN, JR ;
MATSUMOTO, AM ;
RIVIER, JE ;
BREMNER, WJ .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1994, 79 (02) :561-567
[5]   ENDOGENOUS SEX-HORMONES AND CARDIOVASCULAR-DISEASE IN MEN - A PROSPECTIVE POPULATION-BASED STUDY [J].
BARRETTCONNOR, E ;
KHAW, KT .
CIRCULATION, 1988, 78 (03) :539-545
[6]   LOWER ENDOGENOUS ANDROGEN LEVELS AND DYSLIPIDEMIA IN MEN WITH NON-INSULIN-DEPENDENT DIABETES-MELLITUS [J].
BARRETTCONNOR, E .
ANNALS OF INTERNAL MEDICINE, 1992, 117 (10) :807-811
[7]   DYNAMIC CHANGES OF SERUM-LIPOPROTEINS IN CHILDREN DURING ADOLESCENCE AND SEXUAL-MATURATION [J].
BERENSON, GS ;
SRINIVASAN, SR ;
CRESANTA, JL ;
FOSTER, TA ;
WEBBER, LS .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1981, 113 (02) :157-170
[8]   USEFULNESS OF SEX STEROID-HORMONE LEVELS IN PREDICTING CORONARY-ARTERY DISEASE IN MEN [J].
CAULEY, JA ;
GUTAI, JP ;
KULLER, LH ;
DAI, WS .
AMERICAN JOURNAL OF CARDIOLOGY, 1987, 60 (10) :771-777
[9]   RELATION BETWEEN PLASMA HIGH-DENSITY LIPOPROTEIN CHOLESTEROL AND SEX-HORMONE CONCENTRATIONS IN MEN [J].
DAI, WS ;
GUTAI, JP ;
KULLER, LH ;
LAPORTE, RE ;
FALVOGERARD, L ;
CAGGIULA, A .
AMERICAN JOURNAL OF CARDIOLOGY, 1984, 53 (09) :1259-1283
[10]   THE EPIDEMIOLOGY OF PLASMA TESTOSTERONE LEVELS IN MIDDLE-AGED MEN [J].
DAI, WS ;
KULLER, LH ;
LAPORTE, RE ;
GUTAI, JP ;
FALVOGERARD, L ;
CAGGIULA, A .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1981, 114 (06) :804-816
12345