PROTECTION AGAINST AMANITA-PHALLOIDES BY THE IRIDOID GLYCOSIDE MIXTURE OF PICRORHIZA-KURROA (KUTKIN)

被引：21
作者：
FLOERSHEIM, GL
BIERI, A
KOENIG, R
PLETSCHER, A
机构：
[1] Department of Research, Zentrum für Lehre und Forschung, Kantonsspital, Basel, CH-4031
来源：
AGENTS AND ACTIONS | 1990年 / 29卷 / 3-4期
关键词：
D O I：
10.1007/BF01966472
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Survival of mice after lethal doses of a lyophilizate from Amanita phalloides ('death cap') was markedly increased by pretreatment with single doses of kutkin, a mixture of iridoid glycosides picroside I and kutkoside isolated from the roots of Picrorhiza kurroa. The protective effect of kutkin was comparable to that of silibinin. The curative efficacy of kutkin appeared to be slightly superior. © 1990 Birkhäuser Verlag.
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页码：386 / 387
页数：2
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