ANNOTATIONS AND DOMAIN ANALYSIS OF POLYKETIDE SYNTHASE GENES IN FUNGAL WHEAT PATHOGEN, MYCOSPHAERELLA GRAMINICOLA

被引：0
|
作者：
Khalid, Rozida Mohd [1 ]
Bailey, Andy [2 ]
Cox, R. J. [3 ]
机构：
[1] Univ Kebangsaan Malaysia, Sch Chem Sci & Food Technol, Bangi 43600, Malaysia
[2] Univ Bristol, Sch Biol Sci, Bristol BS8 1TH, Avon, England
[3] Univ Bristol, Sch Chem, Bristol BS8 1TH, Avon, England
来源：
JURNAL TEKNOLOGI | 2015年 / 77卷 / 24期
关键词：
Mycosphaerella graminicola; Septoria leaf blotch; polyketide; polyketide synthase; polyketide-nonribosomal peptide synthetase;
D O I：
暂无
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Mycosphaerella graminicola is an important pathogenic fungus of the wheat that causes Septoria tritici blotch. The genome of M. graminicola has been sequence and each domain of all polyketide synthase enzymes (PKS) was analysed and compared with known sequences from NCBI database. NCBI Basic Local Alignment Search Tool (BLAST) analysis and alignment using Vector NTi software suggested that M. graminicola has 10 PKS and 1 PKSNRPS (nonribosomal peptide synthetase) hybrid, which could be involved in pathogenicity. Out of the 10 polyketide synthase genes, two are non-reducing PKS (NRPKS) and eight are annotated as highly reducing PKS (HRPKS). The NRPKS was labelled as MgPKS1 and MgPKS9. The HR PKS were labelled as MgPKS2, MgPKS3, MgPKS4, MgPKS5, MgPKS6, MgPKS7, and MgPKS8. The PKSNRPS also have a highly reducing PKS as part of the hybrid
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页码：171 / 176
页数：6
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