Frontline brentuximab vedotin in breast implant-associated anaplastic large-cell lymphoma

被引:34
作者
Alderuccio, Juan Pablo [1 ]
Desai, Amrita [1 ]
Yepes, Monica M. [2 ]
Chapman, Jennifer R. [3 ]
Vega, Francisco [3 ]
Lossos, Izidore S. [1 ,4 ]
机构
[1] Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Div Hematol,Dept Med, Miami, FL 33136 USA
[2] Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Dept Radiol, Miami, FL 33136 USA
[3] Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Div Hematopathol,Dept Pathol & Lab Med, Miami, FL 33136 USA
[4] Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Dept Mol & Cellular Pharmacol, Miami, FL 33136 USA
关键词
Breast implant-associated anaplastic large-cell lymphoma and brentuximab vedotin; non-Hodgkin's lymphoma;
D O I
10.1002/ccr3.1382
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Key Clinical Message We report a woman who developed BIA-ALCL 9years after saline implant placement. The lymphoma manifested as a mass lesion associated with axillary lymphadenopathy. She was successfully treated with brentuximab vedotin with minimal toxicity. Brentuximab vedotin may be a promising frontline therapeutic modality for patients with BIA-ALCL.
引用
收藏
页码:634 / 637
页数:4
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