Radiotherapy on hidradenocarcinoma

被引:20
作者
Lalya, Issam [1 ,2 ]
Hadadi, Khalid [1 ]
Tazi, El Mehdi [2 ]
Lalya, Ilham [3 ]
Bazine, Amine [1 ]
Andaloussy, Khalid [1 ]
Elmarjany, Mohamed [1 ]
Sifat, Hassan [1 ]
Hassouni, Khalid [2 ]
Kebdani, Tayeb [2 ]
Mansouri, Hamid [1 ]
Benjaafar, Noureddine [2 ]
Elgueddari, Brahim Khalil [2 ]
机构
[1] Mil Hosp Mohamed V, Dept Radiotherapy, Rabat, Morocco
[2] Natl Inst Oncol, Dept Radiotherapy, Rabat, Morocco
[3] Dept Head & Neck Surg, Casablanca, Morocco
关键词
Hidradenocarcinoma; sweat-gland; rare; surgery; recurrence; megavoltage external beam radiotherapy;
D O I
10.4297/najms.2011.343
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Context : Clear cell Hidradenocarcinoma is a rare carcinoma arising from sweat glands. It is an aggressive tumor that most metastasizes to regional lymph nodes and distant viscera; surgery with safe margins is the mainstay of treatment. Case Report: We report a case of 68-year-old woman who presented with an invasive clear cell hidradenocarcinoma situated in the left parotid area which recurred 5 months after surgery, this recurrence was managed successfully by high-dose irradiation of the tumor bed ( 66 Gy) and regional lymphatic chains (50 Gy), after a follow-up of more than 15 months, the patient is in good local control without significant toxicity. Conclusion : Post operative radiotherapy allows better local control and should be mandatory when histological features predictive of recurrence are present: positive margins, histology poorly differentiated, perineural invasion, vascular and lymphatic invasion, lymph node involvement, and extracapsular spread.
引用
收藏
页码:43 / 45
页数:3
相关论文
共 14 条
[1]   Apocrine gland carcinoma of the axilla - Review of the literature and recommendations for treatment [J].
Chamberlain, RS ;
Huber, K ;
White, JC ;
Travaglino-Parda, R .
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 1999, 22 (02) :131-135
[2]   Hidradenocarcinoma arising from pre-existing hidradenoma [J].
Gouiaa, N. ;
Abbes, K. ;
Fakhfekh, I. ;
Ayadi, L. ;
Bahri, I. ;
Chaari, C. ;
Ellouze, S. ;
Chtourou, I. ;
Makni, S. ;
Sellami-Boudawara, T. .
ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE, 2008, 135 (10) :714-715
[3]   Sweat-gland tumours: A clinical review of cases in one centre over 20 years [J].
Hall, J ;
Knee, G ;
A'Hern, RP ;
Clarke, J ;
Glees, JP ;
Ford, HT ;
Eeles, RA .
CLINICAL ONCOLOGY, 2006, 18 (04) :351-359
[4]  
HARARI PM, 1990, CANCER, V65, P1737, DOI 10.1002/1097-0142(19900415)65:8<1737::AID-CNCR2820650813>3.0.CO
[5]  
2-Q
[6]  
KEASBEY LE, 1954, CANCER, V7, P934, DOI 10.1002/1097-0142(195409)7:5<934::AID-CNCR2820070519>3.0.CO
[7]  
2-5
[8]  
Moutaoui L, 2007, ANN DERMATOL VENER, V134, P91, DOI [10.1016/S0151-9638(07)89154-X, DOI 10.1016/S0151-9638(07)89154-X]
[9]  
Requena L., 2006, WHO CLASSIFICATION T
[10]  
Terhaard CH, 2004, PRINCIPLES PRACTICE