Paravalvular regurgitation after transcatheter aortic valve replacement: Diagnosis, clinical outcome, preventive and therapeutic strategies

被引：20

作者：

Dvir, Danny ^{[1
]}

Barbash, Israel M. ^{[1
]}

Ben-Dor, Itsik ^{[1
]}

Torguson, Rebecca ^{[1
]}

Badr, Salem ^{[1
]}

Minha, Sa'ar ^{[1
]}

Pendyala, Lakshmana K. ^{[1
]}

Loh, Joshua P. ^{[1
]}

Pichard, Augusto D. ^{[1
]}

Waksman, Ron ^{[1
]}

机构：

[1] MedStar Washington Hosp Ctr, Intervent Cardiol, 110 Irving St NW,Suite 4B-1, Washington, DC 20010 USA

来源：

CARDIOVASCULAR REVASCULARIZATION MEDICINE | 2013年 / 14卷 / 03期

关键词：

Aortic valve stenosis; Transcatheter aortic valve implantation; Paravalvular regurgitation;

D O I：

10.1016/j.carrev.2013.02.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Paravalvular regurgitation is a common, potentially life-threatening complication of transcatheter aortic valve replacement. Previous studies report a 65%-94% rate of paravalvular leakage after transcatheter implantation, mostly of mild degree. The rate of significant (>= +2) paravalvular regurgitation varies in large clinical trials, and is associated with worse clinical outcome. There is less agreement regarding the significance of mild regurgitation (grade 1+). There are anatomical and procedural correlates for paravalvular leak-most importantly, severe valve calcification, patient prosthetic mismatch, and device malposition. The following review details the current knowledge on paravalvular regurgitation after transcatheter aortic valve replacement, including diagnosis, correlates, clinical outcome, preventive and therapeutic strategies related to this complication. (C) 2013 Published by Elsevier Inc.

引用

页码：174 / 181

页数：8

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