Prolactinoma with bromocriptine treatment. Long-term follow-up

Prolactinomas are a common cause of sexual disfunction and reproduction. Women present amenorrhoea, galactorrea or sterility and men impotence, sterility or libido diminution. Dopaminergic agonists are commonest elect ion in medical treatment of this disease, the most well-known is the bromocriptine. In U.S.A, bromocriptine and pergolide have been accepted several years ago, and recently cabergoline was added to the list; anyone of the three dopaminergic agonists standardizes the prolactose levels and the size of the tumor is reduced 70% in six months. The present work describes the behavior during 10 years of a group of patients with adenoma of hipofisis that were dealt with bromocriptine. We conclude that bromocriptine is safe and effective and represents a dopaminergic agonist well tolerated for the treatment in men and women, in whom gestation is not obtained.