GLYCOSAMINOGLYCAN DISTRIBUTION IN ATHEROSCLEROTIC SAPHENOUS-VEIN GRAFTS

被引：20
作者：
MARQUEZINI, MV
STRUNZ, CMC
DALLAN, LAO
TOLEDO, OMS
机构：
[1] ESCOLA PAULISTA MED, DEPT MORPHOL, BR-04023062 SAO PAULO, BRAZIL
[2] UNIV SAO PAULO, SCH MED, PRO SANGUE FDN HEMOCTR SAO PAULO, BR-05508 SAO PAULO, BRAZIL
[3] UNIV SAO PAULO, SCH MED, CLIN LAB, BR-05508 SAO PAULO, BRAZIL
[4] UNIV SAO PAULO, SCH MED, INST HEART, DIV SURG, BR-05508 SAO PAULO, BRAZIL
来源：
CARDIOLOGY | 1995年 / 86卷 / 02期
关键词：
ATHEROSCLEROSIS; GLYCOSAMINOGLYCANS; SAPHENOUS VEIN GRAFT; REVASCULARIZATION;
D O I：
10.1159/000176860
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Glycosaminoglycan composition of normal saphenous veins and atherosclerotic saphenous vein grafts is reported. Dermatan sulfate is the main glycosaminoglycan present in both normal saphenous veins and saphenous vein grafts. These tissues also contain chondroitin sulfate and heparan sulfate. Although the total amount of glycosaminoglycans decreased in the grafts (compared with normal saphenous veins), the grafts showed an increase in the relative amounts of dermatan sulfate and chondroitin sulfate. Heparan sulfate was decreased, compared with normal controls. These findings suggest the involvement of blood vessel glycosaminoglycans (not only the arterial glycosaminoglycans) in the process of atherosclerosis.
引用
收藏
页码：143 / 146
页数：4
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